Results 31 to 40 of about 347,172 (240)

Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance

PCN Reports
Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation.
Yu Tamada, Takeshi Inoue, Atsushi Sekine, Hiroyuki Toda, Minoru Takeshima, Masaaki Sasaki, Yota Fujimura, Susumu Ohmae   +7 more
doaj   +1 more source

Acute inflammation and psychomotor slowing: Experimental assessment using lipopolysaccharide administration in healthy humans

Brain, Behavior, & Immunity - Health, 2020
Data from clinical and cross-sectional studies suggest that inflammation contributes to psychomotor slowing and attentional deficits found in depressive disorder. However, experimental evidence is still lacking.
Analena Handke, John Axelsson, Sven Benson, Karoline Boy, Vera Weskamp, Till Hasenberg, Miriam Remy, Johannes Hebebrand, Manuel Föcker, Alexandra Brinkhoff, Meike Unteroberdörster, Harald Engler, Manfred Schedlowski, Julie Lasselin   +13 more
doaj   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Motor versus Psychomotor? Deciphering the Neural Source of Psychomotor Retardation in Depression

Advanced Science
Major depressive disorder (MDD) is characterized by psychomotor retardation whose underlying neural source remains unclear. Psychomotor retardation may either be related to a motor source like the motor cortex or, alternatively, to a psychomotor source ...
Xue Mei Song, Dong‐Yu Liu, Dusan Hirjak, Xi‐Wen Hu, Jin‐Fang Han, Anna Wang Roe, De‐Zhong Yao, Zhong‐Lin Tan, Georg Northoff   +8 more
doaj   +1 more source

Types ofpsychomotor developmental disorders inchildren before theage of3 years and the meaning of the early intervention for thechild’s future development – preliminary research

Psychiatria i Psychologia Kliniczna, 2012
Aim of the study: The analysis of the types of developmental disorders in early childhood. Material and methods: Seventy-one children at the age from 7 days to 3 years who came to The Early Intervention Centre for Handicapped Children “Give the Chance”
Anna Klimek, Anna Górska, Marzenna Radecka, Emilia Podgórska, Ewa Zarzecka   +4 more
doaj  

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou, Gillian I. Rice, James O'Sullivan, Ben Parker, Ian N. Bruce, Emma Burkitt‐Wright, Tracy A. Briggs   +6 more
wiley   +1 more source

Comparing Cognitive Functions and Psychosocial Functioning of Euthymic Patients Having Bipolar Mood Disorder with Healthy Controls: A Cross-sectional Study

Annals of Indian Psychiatry
Background: Bipolar disorder is a chronic mental disorder characterized by mania and depression with intervening periods of euthymia. Although cognitive impairments are associated with acute episodes, these do seem to persist in lower degree during ...
Divya Anidharan Rani, Shashwath M. Sathyanath, Ravichandra Karkal, Rohan Dilip Mendonsa, Anil Kakunje   +4 more
doaj   +1 more source

The functional anatomy of psychomotor disturbances in major depressive disorder

Frontiers in Psychiatry, 2015
Psychomotor disturbances (PMD) are a classic feature of depressive disorder that provide rich clinical information. The aim our narrative review was to characterize the functional anatomy of PMD by summarizing findings from neuroimaging studies. We found
Benny eLiberg, Benny eLiberg, Christoffer eRahm, Christoffer eRahm   +3 more
doaj   +1 more source

Homozygous Achondroplasia With Long‐Term Survival: Growth Patterns, Medical Interventions, and Practice Implications

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Homozygous achondroplasia is widely considered perinatal lethal by the medical community. In this case series, we report two children from a single family with longer‐term survival. One child lived for 17 months and the other was 60 months at the time of publication.
Hannah Singerline, Jason Laufman, Kimberly Wallis, Michelle Merrill   +3 more
wiley   +1 more source