Results 51 to 60 of about 347,172 (240)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Sensorimotor performance in euthymic bipolar disorder: the MPraxis (PennCNP) analysis

Brazilian Journal of Psychiatry, 2014
Background: Sensorimotor deficits are an important phenomenological facet observed in patients with bipolar disorder (BD). However, there is little research on this topic.
Maila de C. Neves, Maicon R. Albuquerque, Fernando S. Neves, Guilherme M. Lage, Leandro Malloy-Diniz, Rodrigo Nicolato, Humberto Corrêa   +6 more
doaj   +1 more source

Postictal self‐removal of intracerebral electrodes during stereoelectroencephalography monitoring: A case series

Epileptic Disorders, EarlyView.
Abstract Epilepsy surgery remains the most effective treatment for focal drug‐resistant epilepsy, and stereoelectroencephalography (SEEG) is increasingly used to define the epileptogenic‐zone network (EZN) and guide curative or palliative interventions.
Ionuț‐Flavius Bratu, Romain Carron, Julia Makhalova, Stanislas Lagarde, Fabrice Bartolomei   +4 more
wiley   +1 more source

Classic imaging features of L-2-hydroxyglutaric aciduria in young adult presenting as seizures associated with fever

Annals of Indian Academy of Neurology, 2020
L-2 Hydroxyglutaric aciduria is a rare metabolic disorder which is autosomal recessive in inheritance. It is characterised by the increased urinary excretion of L-2 hydroxyglutaric acid and the diagnosis is based on the increased levels of the L-2 ...
Suresh Kumar, Shikha Bhatia, Mukesh Surya, Sanjiv Sharma   +3 more
doaj   +1 more source

Executive functions and self‐limited epilepsy with centro‐temporal spikes: A scoping review

Epileptic Disorders, EarlyView.
Abstract Executive functions are a set of high‐level cognitive processes necessary for planning, organization, decision‐making, self‐control, and attention, and are carried out in the anterior frontal lobes. An impairment in executive functioning might present as difficulties in planning and organizing activities, in attention and concentration, in ...
Edoardo Fino, Martina Calì, Sara Senese, Simona Pellacani, Viola Margheri, Chiara Pecini, Carmen Barba   +6 more
wiley   +1 more source

Association Between Obstetric Risk Level and Psychomotor Development Impairments in Children Under Five Years

Revista de Investigación e Innovación en Ciencias de la Salud
Introduction. Psychomotor development in early childhood is a key indicator of health and neurodevelopmental status. Perinatal risk factors can compromise this process, influencing the child's functional prognosis.
AdrianaEdit MinietCastillo, Jorge Luis Anaya-González, Jonathan E Muñoz Zambrano, Erlen Carmona Álvarez-Builla   +3 more
doaj   +1 more source

Differential Neural Dynamics in Psychomotor Retardation and Agitation of Depression. [PDF]

Hum Brain Mapp
This study investigates the dynamic functional connectivity underlying depression with psychomotor disturbance. Findings identified a differential lag propagation pattern between agitated and retarded depression related to the somatomotor network.
Liang Q, Xu Z, Chen S, Lin S, Lin X, Li Y, Zhang Y, Peng B, Hou G, Qiu Y, Northoff G.   +10 more
europepmc   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

A rare case of 2q37 microdeletion with Albright hereditary osteodystrophy-like phenotype

The Turkish Journal of Pediatrics, 2011
Chromosome 2q37 microdeletion syndrome is a rare disorder characterized by mild-moderate psychomotor and growth retardation, autistic-like behavior, Albright hereditary osteodystrophy-like metacarpal/metatarsal shortening, and facial ...
Pelin Ozlem Simşek-Kiper, Gülen Eda Utine, Yasemin Alanay, Dilek Aktaş, Mehmet Alikaşifoğlu, Koray Boduroğlu   +5 more
doaj  

Cognitive abilities and psychosocial functioning in bipolar disorder: findings from the BIPLONG study

Frontiers in Human Neuroscience
BackgroundBipolar disorder is associated with impairments in cognition and psychosocial functioning. Although these impairments occur frequently, often persist during euthymic times, and worsen quality of life, the impact of cognitive abilities on ...
Elena M. D. Schönthaler, Nina Dalkner, Tatjana Stross, Susanne Bengesser, Julia Ilic, Frederike Fellendorf, Alexander Finner, Eva Fleischmann, Alfred Häussl, Johanna Georgi, Alexander Maget, Melanie Lenger, Annamaria Painold, Martina Platzer, Robert Queissner, Franziska Schmiedhofer, Stefan Smolle, Adelina Tmava-Berisha, Eva Z. Reininghaus   +18 more
doaj   +1 more source