Results 211 to 220 of about 489,431 (300)

Novel Variants in KMT2C Further Support a Neurodevelopmental Disorder Distinct From Kleefstra and Kabuki Syndromes

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
Sedlackova et al. describe detailed phenotypes of three patients with novel variants in the KMT2C gene. After detailed phenotypic analysis, we found that our patients have phenotypes very similar to those previously described as KMT2C‐related Kleefstra syndrome 2, and thus further extend the list of KMT2C causal variants.
Lucie Sedláčková   +3 more
wiley   +1 more source

Real‐time experience: A systematic review of ecological momentary assessments of everyday functioning in major depressive disorder

open access: yesAustralian Occupational Therapy Journal, Volume 73, Issue 2, April 2026.
Abstract Introduction Major depressive disorder (MDD) is a prevalent, episodic and recurrent condition that adversely affects function across everyday life. Recent studies highlight the importance of everyday function in MDD treatment. Given the dynamic nature of everyday functioning, using comprehensive and real‐time data collection, such as ...
Shani Volovic‐Shushan   +3 more
wiley   +1 more source

Lifetime Mixed Depression and Childhood Trauma in Individuals With Bipolar Disorders

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 4, Page 290-300, April 2026.
ABSTRACT Background and Aims Mixed Depression (MxD), characterized by the co‐occurrence of depressive and excitatory symptoms, is a prevalent yet often underdiagnosed presentation in bipolar disorders (BD), with significant implications for prognosis and treatment. Childhood trauma is a key environmental risk factor associated with a more severe course
Francesca Bardi   +8 more
wiley   +1 more source

Infants' General Movements Were Not Affected by Exposure to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infections

open access: yesActa Paediatrica, Volume 115, Issue 4, Page 913-922, April 2026.
ABSTRACT Aim Prenatal maternal infections may impair infant brain development. This study investigated the effect of maternal infections with the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during pregnancy on infant neurodevelopment by assessing general movements (GMs).
Kathrin Neumayr   +14 more
wiley   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1539-1556, April 2026.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang   +2 more
wiley   +1 more source

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