Results 221 to 230 of about 489,431 (300)

Schizophrenia and catatonia: from ICD-10 to ICD-11. [PDF]

open access: yesNervenarzt
Nickl-Jockschat T   +3 more
europepmc   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen   +2 more
wiley   +1 more source

Portrait of a Spectrum: Clinical and Genetic Characterization of a Large Cohort of Chromatinopathies—30 Years' Experience From a Third Level Center

open access: yesClinical Genetics, Volume 109, Issue 4, Page 707-716, April 2026.
Chromatinopathies (CP) are a growing group of rare genetic disorders characterized by cognitive deficits and growth abnormalities. This is the largest collection of CP to date, contributing to a deeper understanding of the landscape and diagnosis of these rare diseases, strongly improved by the use of large‐scale sequencing technologies.
Giulia Bruna Marchetti   +16 more
wiley   +1 more source

Weight Bias Interventions for Healthcare Professionals: An Integrative Review

open access: yesJournal of Advanced Nursing, Volume 82, Issue 4, Page 2696-2710, April 2026.
ABSTRACT Aim To describe interventions to mitigate weight bias among practicing healthcare providers and examine their effectiveness. Design An integrative review. Methods The framework of Whittemore and Knafl (2005) was utilised to identify and synthesise studies of weight bias interventions.
Gregory S. Marler   +5 more
wiley   +1 more source

Dopamine dysregulation in major depressive disorder with psychomotor retardation: neurobiological insights and clinical implications

open access: gold
Antonio Maria D’Onofrio   +11 more
openalex   +1 more source

Childhood OSAS and Obesity: Prospective Associations of Anthropometric Markers With Objective Sleep Outcomes in the CHAT Trial

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Obstructive sleep apnea syndrome (OSAS) is characterised by episodic upper airway obstruction that occurs during sleep and is common in children with obesity. The aim of the present study was to analyse the association between baseline anthropometric markers and objective sleep quality measures at follow‐up in school‐aged children with OSAS ...
Catalina Ramírez‐Contreras   +2 more
wiley   +1 more source

Rest‐Activity Rhythms and Cognition in Older Adults With and Without Insomnia

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Insomnia is associated with risk for cognitive deficits. However, the literature assessing cognitive impairments in insomnia is replete with conflicting findings; it is unclear whether individuals with insomnia exhibit impaired cognition or whether specific sleep features consistently predict cognitive performance in insomnia.
Miranda G. Chappel‐Farley   +8 more
wiley   +1 more source

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