Results 61 to 70 of about 489,431 (300)

Executive functions and self‐limited epilepsy with centro‐temporal spikes: A scoping review

open access: yesEpileptic Disorders, EarlyView.
Abstract Executive functions are a set of high‐level cognitive processes necessary for planning, organization, decision‐making, self‐control, and attention, and are carried out in the anterior frontal lobes. An impairment in executive functioning might present as difficulties in planning and organizing activities, in attention and concentration, in ...
Edoardo Fino   +6 more
wiley   +1 more source

Syndrome‐specific and familial imaging traits in juvenile absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Juvenile absence epilepsy (JAE) is an idiopathic generalized epilepsy characterized by absences, generalized tonic–clonic seizures, and cognitive difficulties. In contrast to juvenile myoclonic epilepsy (JME), where distinct functional and structural brain alterations are well established, it remains unclear whether comparable ...
Fenglai Xiao   +15 more
wiley   +1 more source

Expanding the Phenotype of TAB2‐Related Syndrome: The First Case With Cleft Palate and Insights Into Palatal Development

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Alberto De Rosa   +7 more
wiley   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

Executive dysfunction and employment in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Executive dysfunction, affective symptoms, and unemployment are prevalent in patients with epilepsy, yet the relation between these variables remains poorly understood. The present study examined: (1) The relationship between epilepsy‐related variables, affective symptoms, and executive functions (EFs); and (2) how these variables ...
Lisa E. Hauger   +6 more
wiley   +1 more source

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add‐on trials in drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Most antiseizure medications (ASMs) have been discovered by testing in animal models, which are generally thought to predict antiseizure activity in patients. However, it is not known whether any of these models (or a combination of models) can predict whether a novel ASM exhibits higher clinical efficacy in focal drug‐resistant ...
Wolfgang Löscher, Pavel Klein
wiley   +1 more source

Comparison of psychomotor development screening test and clinical assessment of psychomotor development

open access: yesActa Clinica Croatica, 2016
Numerous adverse factors are acting in the prenatal, perinatal and postnatal period of life and may be the cause of later mild or severe deviations from normal psychomotor development.
Goranka Radmilović   +2 more
doaj   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Detection of Psychomotor Retardation in Youth Depression: A Machine Learning Approach to Kinematic Analysis of Handwriting

open access: yesApplied Sciences
Depressive disorders significantly impact individuals worldwide, including children and adolescents. Despite their widespread occurrence, early and precise diagnosis of depressive disorders remains a complex and challenging task, particularly in younger ...
Vladimir Džepina   +6 more
doaj   +1 more source

Teaching Occlusal Splints in the Digital Age: Comparing Student Experiences with Conventional and CAD/CAM Workflows

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Background The teaching of occlusal splint therapy in dental education is evolving with the integration of digital workflows. Although digital tools offer operational advantages, conventional methods remain pedagogically relevant. Understanding students’ perceptions of both approaches is essential for guiding curriculum innovation.
Marcelo José Palma‐Fernandes   +6 more
wiley   +1 more source

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