Results 261 to 270 of about 512,327 (345)

Case‐based learning (CBL) in undergraduate health professions education: A realist review

open access: yesMedical Education, EarlyView.
Abstract Introduction Case‐based learning (CBL) has been adopted internationally, although there is significant heterogeneity in implementation and delivery. It is unclear how this pedagogical approach is experienced across contexts, among different groups of students, and the important aspects of implementation. The aim of this study was to understand
Ronan Daly   +5 more
wiley   +1 more source

Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda   +6 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions

open access: yesExperimental Physiology, EarlyView.
Abstract Long‐duration spaceflight impacts essentially every system in the human body, resulting in multisystem deconditioning that might impair the health and performance of crewmembers, particularly on long‐duration exploration missions to Mars. In this review, we apply the sport science model of athlete monitoring, testing and training to astronauts;
Luke DeVirgiliis   +8 more
wiley   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Respiratory acclimatization and psychomotor performance after rapid ascent and during 3 weeks at 3100 m. A prospective cohort study in healthy

open access: yes
Muralt L   +8 more
europepmc   +1 more source

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