Results 181 to 190 of about 409,123 (298)

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Executive functions and psychopathology: A transdiagnostic network analysis. [PDF]

PLoS One
Ganai UJ, Bhushan B.
europepmc   +1 more source

A review of approaches and models in psychopathology conceptualization research

, 2023
Nicholas R. Eaton, Laura F. Bringmann, Timon Elmer, Eiko I. Fried, Miriam K. Forbes, Ashley L. Greene, Robert F. Krueger, Roman Kotov, Patrick D. McGorry, Cristina Mei, Monika A. Waszczuk   +10 more
openalex   +2 more sources

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Development and Comparability of Internalizing and Externalizing Symptom Spectra From Adolescence to Young Adulthood. [PDF]

Int J Methods Psychiatr Res
Birgel V, Rapp M, Tschorn M, Hölling H, Cohrdes C.   +4 more
europepmc   +1 more source

Absence of Systematic Effects of Internalizing Psychopathology on Learning Under Uncertainty

Muhammad H Satti, Katharina Wille, Matthew R. Nassar, Radoslaw Martin Cichy, Nicolas W. Schuck, Peter Dayan, Rasmus Bruckner   +6 more
openalex   +1 more source

Examining the shared etiology of psychopathology with genome-wide association studies

, 2023
Travis T. Mallard, Andrew D. Grotzinger, Jordan W. Smoller   +2 more
openalex   +2 more sources

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Examining Causal Pathways to Suicidal Ideation and Nonsuicidal Self-Injury in the Adolescent Brain Cognitive Development Study. [PDF]

Suicide Life Threat Behav
Yan M, Kummerfeld E, Rawls E, Cullen KR, Klimes-Dougan B.   +4 more
europepmc   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

Advanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang, Ruifeng Li, Wenwen Yu, Anan Li, Xiangning Li, Mingchao Yan, Lei Xie, Qingrun Zeng, Xueyan Jia, Shuxin Wang, Ronghui Ju, Feng Chen, Qingming Luo, Hui Gong, Andrew Zalesky, Xiaoquan Yang, Yuanjing Feng, Zheng Wang   +17 more
wiley   +1 more source