Results 181 to 190 of about 397,654 (297)

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

open access: yesAdvanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo   +17 more
wiley   +1 more source

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

open access: yesAdvanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan   +12 more
wiley   +1 more source

Brief and Valid? Testing the SDQ for Measuring General Psychopathology in Children. [PDF]

open access: yesBehav Sci (Basel)
Copoví-Gomila V   +4 more
europepmc   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

open access: yesAdvanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He   +6 more
wiley   +1 more source

Vulnerability to stress and psychopathology among third year medical students

open access: diamond, 2015
João Gama Marques   +3 more
openalex   +1 more source

BROAD‐NESS Uncovers Dual‐Stream Mechanisms Underlying Predictive Coding in Auditory Memory Networks

open access: yesAdvanced Science, EarlyView.
BROADband Network Estimation via Source Space (BROAD‐NESS) is a flexible analytical pipeline for identifying large‐scale brain networks from event‐related, source‐reconstructed MEG data, with a focus on auditory predictive and memory processes. BROAD‐NESS integrates a suite of complementary tools, including PCA‐based decomposition, phase space, and ...
Leonardo Bonetti   +8 more
wiley   +1 more source

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