Results 51 to 60 of about 1,256,429 (210)

Prevalence and architecture of de novo mutations in developmental disorders

, 2017
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important genes.
Deciphering Developmental Disorders Study (21878732)
core   +6 more sources

Epigenetic signatures of attention problems in youth with childhood exposure to family and community violence

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The link between violence‐related epigenetic changes and attentional problems (APs) is still not well understood. This article examines if exposure to family and community violence during childhood and adolescence may shape DNA methylation patterns associated with attention in youth.
Renata Queiroz Ramos, Adriane Feijó Evangelista, Cosme Marcelo Furtado Passos da Silva, Fernanda Serpeloni, Joviana Quintes Avanci, Natasha Reis Lacerda, Simone Gonçalves de Assis   +6 more
wiley   +1 more source

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of eating disorders.

, 2011
The treatment of eating disorders is a complex process that relies not only on the use of psychotropic drugs but should include also nutritional counselling, psychotherapy and the treatment of the medical complications, where they are present.
J. Treasure, P. Monteleone, THE WFSBP TASK FORCE ON EATING DISORDERS, M. Aigner   +3 more
core   +1 more source

Too Far, Too Close: Attachment and Early Relational Correlates of Pathological Affective Dependence and Fear of Intimacy

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT Specific relational risk conditions may increase vulnerability to dysfunctional, coercive, or unsafe intimate relationships in adulthood. Pathological Affective Dependence (PAD) and Fear of Intimacy (FoI) represent two clinically relevant relational conditions associated with difficulties in adult intimacy.
Carolina Papa, Erica Pugliese, Claudia Perdighe, Francesco Mancini, Marcela Matos   +4 more
wiley   +1 more source

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 [PDF]

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
GBD 2021 Nervous System Disorders Collaborators, GBD 2021 Nervous System Disorders Collaborators,   +1 more
core   +1 more source

Knowledge, Attitude, and Practice Among Practicing Dentists Toward Inclusion of Patients Suffering from Psychosomatic Disorders in their Practice: A Cross-Sectional Study

Journal of Indian Academy of Oral Medicine and Radiology
Background: In recent decades, particularly following the coronavirus disease 2019 (COVID-19) pandemic, there has been growing uncertainty in individuals’ way of life, significantly increasing the need for healthcare providers to acquire knowledge about ...
Medhana M. Mangaonker, Manisha M. Khorate, Pratiksha Keny, Sushmita Wayadande   +3 more
doaj   +1 more source

Splenic contraction associated with sudden, transient hypotension and sympathoexcitation in humans

Experimental Physiology, EarlyView.
Abstract The spleen is traditionally recognised for its roles in immunity and blood filtration, and it is known to contract and release stored erythrocytes in hypoxic conditions. Recent findings suggest that the spleen may also contribute to cardiovascular regulation.
Angelica Lodin‐Sundström, Gabriel Axelsson, Lisa Ljungberg, Mats H. Linér, Bodil Sjögreen, Johan P. A. Andersson   +5 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Pediatric epilepsy and comorbid reading disorders, math disorders, or autism spectrum disorders: Impact of epilepsy on cognitive patterns [PDF]

, 2015
Introduction: In pediatric epilepsy, comorbidities are reported to be frequent. The present study focusedon the cognitive patterns of children with isolated epilepsy, children with isolated neurodevelopmental disorders (reading disorders, math disorders,
Zijlstra, B.J.H., de Jong, P.F., van Iterson, L., de Jong, P.F.; id_orcid, Zijlstra, B.J.H.; id_orcid   +4 more
core   +2 more sources

Adolescência vulnerável: fatores biopsicossociais relacionados ao uso de drogas

Revista Bioética
As modificações físicas, psíquicas e sociais da adolescência aprofundam a condição de vulnerabilidade e aumentam o risco de início precoce do uso de substâncias psicoativas (SPA).
Ana Luiza Portela Bittencourt, Lucas Garcia França, José Roberto Goldim   +2 more
doaj   +1 more source