Results 51 to 60 of about 90,738 (349)

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Neuronal congruency effects in macaque prefrontal cortex

Nature Communications, 2022
Stimulus-induced conflicts impair behavior in conflict tasks resulting in a phenomenon known as the behavioral congruency effect. Here, the authors investigate the neural underpinnings of this phenomenon and report a neuronal congruency effect in macaque
Tao Yao, Wim Vanduffel
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Epigenetic Modifications lead towards Neurodegeneration

International Journal of Endorsing Health Science Research, 2020
Background: The foremost factor involved in Neurodegeneration is the impact of epigenetic modifications; through its nature to epigenetically mark the neuron-associated genes, also, by affecting cognitive functions and damaging neurons that promote ...
Anna Askari, Shamoon Noushad, Sadaf Ahmed, Faizan Mirza, Syed A. Aziz   +4 more
doaj   +1 more source

Reward positivity elicited by predictive cues

, 2011
A recent theory holds that a component of the human event-related brain potential called the reward positivity reflects a reward prediction error signal. We investigated this idea in gambling-like task in which, on each trial, a visual stimulus predicted
Holroyd, Clay, Krigolson, Olav E., Lee, Seung   +2 more
core   +1 more source

The effects of the spontaneous presence of a spouse/partner and others on cardiovascular reactions to an acute psychological challenge [PDF]

, 2006
The presence of supportive others has been associated with attenuated cardiovascular reactivity in the laboratory. The effects of the presence of a spouse and others in a more naturalistic setting have received little attention.
Allen M. T., Andrews F. M., Berkman L. F., Brown P. C., Christenfeld N., Fox A. J., Gerin W., Gerin W., Glynn L. M., Helsing K. J., House J. S., Kamarck T. W., Kamarck T. W., Kamarck T. W., Kors D. J., Lepore S. J., Lepore S. J., Markovitz J. H., Marmot M. G., Orth-Gomer K., Rosengren A., Sheffield D., Smith T. W., Smith T. W., Snydersmith M., Treiber F. A., Wright R. A.   +26 more
core   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Electrodermal activity moderates the relationship between depression and suicidal ideation in a group of patients with anxiety and depressive symptoms

Journal of Affective Disorders Reports, 2023
Purpose: Being suicide a serious global issue, it's urgent to identify the involved factors and possibly precursors. In our study, it was hypothesized that autonomic hyperactivation might have a moderating role in the relationship between symptoms of ...
Carlo Pruneti, Alice Fiduccia, Sara Guidotti   +2 more
doaj   +1 more source

Neural mechanisms of affective instability and cognitive control in substance use

, 2019
Objective: We explored the impact of affect on cognitive control as this relates to individual differences in affective instability and substance use.
Bodkyn, Carmen N., Holroyd, Clay
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source