Results 301 to 310 of about 444,703 (391)

Harnessing Small‐Data Machine Learning for Transformative Mental Health Forecasting: Towards Precision Psychiatry With Personalised Digital Phenotyping

Med Research, EarlyView.
Small‐data machine learning models (e.g., TabPFN, GPs) harness sparse digital phenotyping streams from wearables and smartphones to forecast individualized mental health trajectories, enabling proactive interventions through uncertainty‐aware predictions and closed‐loop clinical integration. ABSTRACT Advances in digital phenotyping have opened the door
Peng Wang, Hongjun Liu, Yiming Shi, Ao Liu, Qingyu Zhu, Irina Albu, Maja Pacholec, Lulu Cheng, Xu Sun, Xinli Chi   +9 more
wiley   +1 more source

Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech. [PDF]

Transl Psychiatry
Olah J, Wong WLE, Chaudhry ARR, Mena O, Tang SX.   +4 more
europepmc   +1 more source

Interpersonal Psychotherapy for the Treatment of Depression in Parkinson's Disease: Results of a Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background Depression is a common nonmotor complication in Parkinson's disease (PD). However, few studies have evaluated the efficacy of first‐line psychological therapies for depression in this patient population. Objectives This randomized controlled trial evaluated the efficacy of interpersonal psychotherapy (IPT), an empirically validated ...
Diana Koszycki, Monica Taljaard, Jacques Bradwejn, Caroline Lee, Giorgio A. Tasca, David A. Grimes   +5 more
wiley   +1 more source

Subcutaneous Foslevodopa as Novel Rescue Therapy for Akinetic Crisis in Parkinson's Disease: A Case Report

Movement Disorders Clinical Practice, EarlyView.
Bendix Labeit, Julius Schulten, Alfons Schnitzler, Christian Johannes Hartmann   +3 more
wiley   +1 more source

Evaluation of Induced Pluripotent Stem Cell‐Derived Dopaminergic Neurons from Siblings with Gaucher Disease Discordant for Parkinsonism

Movement Disorders, EarlyView.
Abstract Background In Gaucher disease (GD), glucocerebrosidase (GCase) deficiency results from biallelic pathogenic GBA1 variants. While GBA1 variants are a major risk factor for Parkinson's disease (PD), most patients with GD never develop parkinsonism.
Ellen Hertz, Krystyna Rytel, Gani Perez, Ying Hao, Ziyi Li, Charis Ma, Kate Andersh, Yue Andy Qi, Emory Ryan, Grisel Lopez, Nahid Tayebi, Ellen Sidransky, Yu Chen   +12 more
wiley   +1 more source

Integrating sleep-related breathing disorders and epigenetics into the genetic landscape of sleep disturbances in psychotic disorders. [PDF]

Psychol Med
Perdigoto S, De Pedro M, Meira E Cruz M.
europepmc   +1 more source

Protective Effects of Genetic Proxies of Cognitive Reserve in Parkinson's Disease: A Longitudinal Multi‐Cohort Study

Movement Disorders, EarlyView.
ABSTRACT Background Resilience factors are crucial in the progression of neurodegenerative diseases. However, it remains unclear whether a genetic predisposition to cognitive reserve influences clinical heterogeneity in the prognosis of Parkinson's disease (PD).
Young Eun Huh, Beomjin Jang, Sang‐Hyuk Jung, Dokyoon Kim, Towfique Raj, Hong‐Hee Won   +5 more
wiley   +1 more source

From Idealist to Realist-Designing and Implementing Shared Decision-Making Interventions in the Choice of Antipsychotic Prescription in People Living with Psychosis (SHAPE): A Realist Review. [PDF]

Schizophr Bull
Fitzgerald I, Sahm LJ, Maidment I, Wallace E, Zisman-Ilani Y, Højlund M, O'Dwyer S, Ní Dhubhlaing C, Crowley EK, Howe J.   +9 more
europepmc   +1 more source

Do Cognitive Subtypes Exist in People at Clinical High Risk for Psychosis? Results From the EU-GEI Study. [PDF]

Schizophr Bull
Gifford G, Avila A, Kempton MJ, Fusar-Poli P, McCutcheon RA, Coutts F, Tognin S, Valmaggia L, de Haan L, van der Gaag M, Nelson B, Pantelis C, Riecher-Rössler A, Bressan R, Barrantes-Vidal N, Krebs MO, Glenthøj B, Ruhrmann S, Sachs G, Rutten BPF, van Os J, Eu-Gei High Risk Study, McGuire P.   +22 more
europepmc   +1 more source

Early intervention for psychosis [PDF]

, 2011
Knapp, Martin, McCrone, Paul, Park, A-La
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