Results 101 to 110 of about 244,881 (307)

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Determinants of psychosocial disorders among caregivers of HIV-infected children in Enugu, Southeast Nigeria

International Journal of Medicine and Health Development, 2019
Background: Human immunodeficiency virus (HIV) infection is a global pandemic. Nigeria has the highest burden of pediatric HIV worldwide. HIV-infected children and their caregivers are predisposed to significant psychosocial disorder.
Ikechukwu F Ogbonna, Ngozi C Ojinnaka, Ifeoma J Emodi, Nnaemaka A Ikefuna   +3 more
doaj   +1 more source

Psychosocial Determinants of Romantic Inclination Among Indian Youth

Interpersona: An International Journal on Personal Relationships, 2017
The present study was conducted with the aim of understanding the psychosocial determinants of romantic inclination among youth in India. We involved 779 student participants from a large central university in south India in the age range of 18-24 years.
D. Barani Ganth, S. Kadhiravan
openaire   +2 more sources

The pain of low status: the relationship between subjective socio-economic status and analgesic prescriptions in a Scottish community sample [PDF]

, 2016
There is a strong positive relationship between objective measures of socioeconomic status (OSS) and general health. However, there is an increasing interest in the relationship between health and subjective socioeconomic status (SSS), which describes ...
Fabio Sani, Fuentes M., Joint Formulary Committee, Juliet Ruth Helen Wakefield, Melzack R., Michael Norbury, Pat Dugard, Peterson C., Scottish Government, Scottish Intercollegiate Guidelines Network, Vishnu Madhok   +10 more
core   +4 more sources

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Psychosocial Determinants of Successful Voice Rehabilitation After Laryngectomy

Journal of the Chinese Medical Association, 2007
This study gives an overview of publications on factors that are associated with the outcome of voice rehabilitation after laryngectomy. A systematic literature review was conducted. Fifty-six manuscripts were analyzed regarding the parameters investigated, the number of participants included, the study designs used, the assessment instruments, and the
Singer, Susanne, Merbach, Martin, Dietz, Andreas, Schwarz, Reinhold   +3 more
openaire   +2 more sources

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Study protocol: SWING – social capital and well-being in neighborhoods in Ghent [PDF]

, 2015
Background: Investing in social capital has been put forth as a potential lever for policy action to tackle health inequity. Notwithstanding, empirical evidence that supports social capital's role in the existence of health inequity is limited and ...
Hardyns, Wim, Pauwels, Lieven, Vyncke, Veerle, Willems, Sara   +3 more
core   +2 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Psychosocial Care Needs of Melanoma Survivors: Are They Being Met?

PLoS ONE, 2015
Patients who have survived malignant melanoma for more than five years may lack the opportunity to talk about their burden. As a consequence their psychosocial care needs remain undetected and available supportive interventions may not be utilised ...
Sabine Fischbeck, Barbara H Imruck, Maria Blettner, Veronika Weyer, Harald Binder, Sylke R Zeissig, Katharina Emrich, Peter Friedrich-Mai, Manfred E Beutel   +8 more
doaj   +1 more source