Results 51 to 60 of about 392,051 (301)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Culturally and trauma-informed music therapy: approaches for school settings illustrated through descriptive cases from Norway, the United States and South Africa

Frontiers in Psychiatry
IntroductionMusic-based wellness programs have emerged as promising approaches for supporting youth development and psychosocial wellbeing in school settings, particularly for adolescents exposed to trauma. This paper examines how music therapy and music-
Kathleen M. Murphy, Viggo Krüger, Karyn Stuart-Röhm, Karyn Stuart-Röhm, Colton Thorn, Sarah Berry   +5 more
doaj   +1 more source

A case report of COVID-19 colitis and a sports medicine driven community outreach program that contributed to a successful outcome

Journal of Community Hospital Internal Medicine Perspectives, 2021
This case illustrates a lesser seen presentation of SARS-CoV-2 (henceforth to be termed COVID-19): acute ascending colitis in the community setting. In a broader context, however, this case demonstrates the importance of community, spirituality and a ...
J. Tabacco, M. Covell, C. Annunziata, H. Najaf Bagy   +3 more
doaj   +1 more source

Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, for the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry Investigators, David A. Cabral, Gaëlle Chédeville, Ciarán M. Duffy, Kerstin Gerhold, Jaime Guzman, Linda Hiraki, Adam M. Huber, Heinrike Schmeling, Natalie J. Shiff, Lori B. Tucker, Julie Barsalou, Daniah Basodan, Michelle Batthish, Roberta A. Berard, Nicholas Blanchette, Gilles Boire, Roxana Bolaria, Alessandra Bruns, David A. Cabral, Sarah Campillo, Tania Cellucci, Mercedes Chan, Gaëlle Chédeville, Amieleena Chhabra, Julie Couture, Paul Dancey, Jean‐Jacques De Bruycker, Erkan Demirkaya, Muhammed Dhalla, Ciarán M. Duffy, Talal El Tal, Tommy Gerschman, Jaime Guzman, Liane Heale, Julie Herrington, Kristin M. Houghton, Adan M. Huber, Andrea Human, Nicole Johnson, Roman Jurencak, Bianca Lang, Claire LeBlanc, Lillian Lim, Lily S. H. Lim, Nadia Luca, Jeanine McColl, Tara McGrath, Tamara McMillan, Megan McPherson, Paivi Miettunen, Kimberly Morishita, Honyan Ng, Jonathan Park, Jean‐Philippe Proulx‐Gauthier, Johannes Roth, Evelyn Rozenblyum, Dax G. Rumsey, Heinrike Schmeling, Rosie Scuccimarri, Gordon Soon, Rebeka Stevenson, Elizabeth Stringer, Herman Tam, Lori B. Tucker, Marinka Twilt, Ruud H. J. Verstegen, Karen Watanabe Duffy   +81 more
wiley   +1 more source

Influence of Gaming Addiction on Psychosocial Well-Being

Cureus
The gaming journey started decades ago, beginning with simple video games and evolving into flexible mobile games that are accessible everywhere and at any time. This review assesses gaming addiction in terms of risk factors and psychosocial consequences. Gaming disorder is a term used to describe a behavioral condition related to abnormal gaming usage.
Menezes, Ritesh G, Nepal, Samata, Bajracharya, Mimosa, Alshammari, Asma A, Moizuddin, Khwaja, Atreya, Alok   +5 more
openaire   +2 more sources

A wellness és spa szolgáltatások fejlődése, napjainkig

, 2021
Amikor el szeretnénk utazni valahová, szinte biztosan szóba kerül az, hogy az adott helyszínen kipróbálunk valamilyen egészségturisztikai szolgáltatást. Legyen az wellness, vagy valamilyen spa kezelés. A wellness maga, egyre inkább elengedhetetlen része
Lakatos, Annabella
core  

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Maternal low-intensity psychosocial telemental interventions in response to COVID-19 in Qatar: study protocol for a randomized controlled trial

Trials, 2021
Introduction As COVID-19 is spreading, new psychological health problems are suspected to be emerging among pregnant women. Higher maternal mental health distress, including perinatal anxiety, depression, and COVID-19-specific phobia, is supposed to be ...
Sarah Naja, Rowaida Elyamani, Mohamad Chehab, Mohamed Siddig, Abdullah Al Ibrahim, Tagreed Mohamad, Rajvir Singh, Iheb Bougmiza   +7 more
doaj   +1 more source

Dimensions of students’ psychosocial well-being and their measurement: Validation of a students’ Psychosocial Well Being Inventory

Europe’s Journal of Psychology, 2010
This paper presents findings from a validation study of a measurement instrument for the dimensions of students’ psychosocial well-being. Researches to date suggest many separate but related dimensions of psychosocial well-being. In the current study, psychosocial well-being is considered to have four dimensions: subjective well-being related to every ...
openaire   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source