Results 31 to 40 of about 48,735 (346)

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

COMMENTARY ON COMMENTARIES: A SPACE FOR DIALOGUE AMONG DIFFERENT PERSPECTIVES [PDF]

open access: yes, 2006
In this commentary we discuss our reactions towards the six contributions on our article “The psychotherapist’s social role under a dialogical perspective: A study of the personal construction of «I as psychotherapist»” (in this issue).
Gonçalves, Miguel   +2 more
core  

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

The General Structure of The Dark Personality of University Students [PDF]

open access: yesInternational Journal of Instructional Technology and Educational Studies
The study aimed to identify the factor structure of the dark personality of university students. The sample consisted of (500) male and female students from the fourth year of university students, their ages ranged between (21 - 22) years with an average
khaled Rafeek Badawy
doaj   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

How secure is the secure base? Romantic attachment, emotion regulation, and psychotherapists’ role as secure base figures

open access: yesResearch in Psychotherapy
In 1988, Bowlby posited that the emotional availability of psychotherapists in establishing a secure base environment is influenced by their personal relational history.
Helena Carvalho   +2 more
doaj   +1 more source

Psychopathological effects of psychostimulant substances and psychotic onset: the difficult process of differential diagnosis between substance-induced psychosis and acute primary psychosis

open access: yesPsychiatria i Psychologia Kliniczna, 2015
Among the psychopathological effects induced by stimulants there can be a variety of psychotic-like experiences that can resolve in a matter of hours or within a few days without clinical treatment, or can instead constitute initial symptoms of a ...
Emanuela Atzori
doaj   +1 more source

A Short History of a Controversial Diagnosis

open access: yesRicerca Psicoanalitica, 2020
This work retraces the history of gender identity, a construct which came to light at the end of the sixties, and whose path we will follow up until the present day.
Alexandro Fortunato   +2 more
doaj   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti   +13 more
wiley   +1 more source

A questions-based investigation of consumer mental-health information [PDF]

open access: yesPeerJ, 2015
Despite the wealth of mental-health information available online to consumers, research has shown that the mental-health information needs of consumers are not being met.
Colleen E. Crangle, Joyce Brothers Kart
doaj   +2 more sources

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