Results 51 to 60 of about 83,228 (255)

The Effect of Online Parent Training With and Without Coaching Support on the Well‐Being of Families of Children With Neurodisabilities: A Randomized Controlled Trial

Autism Research, EarlyView.
ABSTRACT Families of children with neurodisabilities often face significant child behavioral challenges that can affect overall family functioning and well‐being. This randomized controlled trial (RCT) used family resilience theory as the investigative framework to examine the impact of an online parenting program designed to address child behavioral ...
Jeffrey McCrossin, Ali Filali‐Mouhim, Michael Ungar, Karen McEwan, Kathleen O'Grady, Donna Thomson, Parent Advisory Group, Patricia Lingley‐Pottie, Patrick McGrath, Lucyna M. Lach   +9 more
wiley   +1 more source

Psychological interventions for people with psychotic experiences: protocol for a systematic review and meta-analysis

Systematic Reviews, 2019
Background Many people who have common mental disorders, such as depression and anxiety, also have some psychotic experiences. These experiences are associated with higher clinical complexity, poor treatment response, and negative clinical outcomes ...
Emma Soneson, Debra Russo, Clare Knight, Louise Lafortune, Margaret Heslin, Jan Stochl, Alex Georgiadis, Julieta Galante, Robbie Duschinsky, Nick Grey, Leticia Gonzalez-Blanco, Juliet Couche, Michelle Griffiths, Hannah Murray, Nesta Reeve, Joanne Hodgekins, Paul French, David Fowler, Sarah Byford, Mary Dixon-Woods, Peter B. Jones, Jesus Perez   +21 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Proportion of Psychotic Features in Patients With Major Depression and Their Relationship With Depression Severity: A Cross-Sectional Study

Kerala Journal of Psychiatry
Background: Psychotic features like delusions and hallucinations occur in a clinically meaningful subset of depressive episodes. While Western estimates place the prevalence of psychosis in depression at 15–30%, Indian data are limited.
Amrutha C Madhu, Ashfaq U Rahman AM, Uvais NA, Chitra Dilip   +3 more
doaj   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Service user perspectives and experiences of their diagnosis of psychotic major depression: A qualitative study.

PLoS ONE
BackgroundEvidence suggests psychotic major depression can be overlooked in clinical settings and thus lead to delays in diagnosis. There have been multiple theories about why this happens, however no research has investigated this from a service users ...
Emilia May Loane, Norha Vera San Juan, Allan H Young, Oliver Gale-Grant, Margaret Heslin   +4 more
doaj   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source

Abnormal connectivity in the fronto-striatal network in adolescent depression with psychotic symptoms

Child and Adolescent Psychiatry and Mental Health
Background Adolescent depression patients with psychotic symptoms have a worse prognosis and higher risk of suicide compared to those without psychotic symptoms, however, the neurophysiological underlying pathway is still unclear.
Xinlin Huang, Ju Gao, Xiaowei Tang, Yongming Wang, Feng Gao, Jiaming Tian, Shaochen Cheng, Yutong Li, Xiaobin Zhang, Hongyan Sun   +9 more
doaj   +1 more source

A case report of schizoaffective disorder with ritualistic behaviors and catatonic stupor: successful treatment by risperidone and modified electroconvulsive therapy

BMC Psychiatry, 2018
Background Ritualistic behaviors are common in obsessive compulsive disorder (OCD), while catatonic stupor occasionally occurs in psychotic or mood disorders.
Yuanhan Bai, Xi Yang, Zhiqiang Zeng, Haichen Yang   +3 more
doaj   +1 more source