Results 81 to 90 of about 13,518 (258)

In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing

Drug Testing and Analysis, EarlyView.
Δ8‐THC and Δ9‐THC showed comparable metabolic profiles. In contrast, Δ10‐THC underwent extensive glucuronidation and hydroxylation, with only minor formation of a carboxy metabolite, indicating a markedly different metabolic pathway. These differences may increase the risk of misidentification and misinterpretation in cannabis drug testing.
Robert Kronstrand, Henrik Green, Markus Loh, Fabian Rüttimann, Manuela Carla Monti   +4 more
wiley   +1 more source

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

Epilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod, Colin B. Josephson, Samuel Wiebe, The Calgary Comprehensive Epilepsy Program Collaborators, Felippe Borlot, Guillermo Delgado‐García, Paolo Federico, Nathalie Jette, Karl Martin Klein, William Murphy, Neelan Pillay, Andrea Salmon, Shaily Singh, The Epilepsy Surgery Satisfaction Questionnaire Study Group, Mark J. Atkinson, Walter J. Hader, Mark R. Keezer, Oluwaseyi A. Lawal, Sophia Macrodimitris, Kristina Malmgren, Dang K. Nguyen, Scott B. Patten, Tolulope T. Sajobi, Ruby Sharma, Yves Starreveld, José Tellez‐Zenteno, Sandra Wahby   +26 more
wiley   +1 more source

Mortality in functional seizures: Evidence from a large electronic health records dataset

Epilepsia, EarlyView.
Abstract Objective Several studies have found that people with functional seizures (FS) have increased mortality, approaching that of epilepsy (epileptic seizures [ES]). The small numbers of deaths in these studies make it unclear whether they can be attributed to comorbidities. We used a very large electronic health database to compare mortality in FS
Richard A. Kanaan, Rok Berlot, Tom Pollak, Markus Reuber, Stoyan Popkirov   +4 more
wiley   +1 more source

Sleep Health in Bulimia Nervosa: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Research on sleep in bulimia nervosa (BN) is methodologically varied and yields inconsistent findings. This review synthesised BN‐sleep studies and examined whether comorbid mood disorders contribute to sleep disturbance. Method PsycINFO, Medline (Ovid), and Scopus were searched for English or French quantitative studies comparing ...
Samantha Kenny, Malka Hershon, Linda Booij, Rebecca Burdayron, Marie‐Hélène Pennestri   +4 more
wiley   +1 more source

Substances Involved in Human Poisoning a Comparison between Intentional and Accidental Poisoning Cases

مجله اپیدمیولوژی ایران, 2008
Background & Objectives: Self-poisoning is one of the oldest and most common forms of self-harm and a frequent incident of referring to hospital poisoning wards.
SA Azin, A Shahidzadeh Mahani , M Abadi, S Omidvari, A Montazeri   +4 more
doaj  

A Socially Assistive Robot for Outpatient Eating Disorder Waiting‐List Support: A Mixed‐Methods Feasibility Randomised Controlled Trial

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This feasibility randomised controlled trial (RCT) evaluated Purrble, a socially assistive robot for emotion regulation, as a low‐intensity adjunct during waitlist periods in adult eating disorder services. Method Adults waiting for outpatient eating disorder treatment were randomised to four weeks of Purrble use or waitlist‐as‐usual.
Dimitri Chubinidze, Zhuo Li, Ayse Gundogan, Karina L. Allen, Petr Slovak, Kate Tchanturia   +5 more
wiley   +1 more source

PRINCIPIILE CARE GUVERNEAZĂ TRANSPUNEREA ÎN DREPTUL INTERN AL REPUBLICII MOLDOVA A PREVEDERILOR CONVENŢIILOR INTERNAŢIONALE ÎN MATERIE DE COMBATERE A TRAFICULUI ILICIT DE DROGURI ŞI PRECURSORI

Studia Universitatis Moldaviae: Stiinte Sociale, 2007
The principles that govern the transposing to the internal law of Republic of Moldova of the stipulations of the international conventions referring to fighting against the traffic of drugs and their precursors are analyzed in the article.
USM ADMIN
doaj  

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Familial Risk and Resilience Moderate the Association Between Intolerance of Uncertainty and Youth Suicidal Ideation

Journal of Clinical Psychology, EarlyView.
ABSTRACT Background Intolerance of uncertainty (IU), defined as a trait‐like tendency to respond to uncertain situations with negative cognitive, behavioral, and/or physiological reactions, is associated with increased risk for suicidal ideation (SI). Theory and research suggest that family‐level risk and resilience factors may shape how vulnerability ...
Alexa House, Shiane Toleson, Kathryn C. Jenkins, Kayla Kreutzer, Nicholas Allan, K. Luan Phan, Stephanie Gorka   +6 more
wiley   +1 more source

Evaluation and treatment of mental health symptoms among unaccompanied migrant children and adolescents in the United States: A systematic review

JCPP Advances, EarlyView.
Abstract Background Unaccompanied migrant youths are at elevated risk for exposure to trauma and related mental health challenges, but there is minimal evidence guiding best practices. We conducted a systematic review of quantitative studies that examined mental health evaluation and treatment services for unaccompanied migrant youths resettled in the ...
Natan J. Vega Potler, Sebastian Villegas, Dorice Vieira, Sarah M. Horwitz   +3 more
wiley   +1 more source