Results 111 to 120 of about 543 (149)

Bracken (Pteridium aquilinum)-Induced DNA Adducts in Mouse Tissues Are Different From the Adduct Induced by the Activated Form of the Bracken Carcinogen Ptaquiloside

Biochemical and Biophysical Research Communications, 2001
Following treatment with bracken fern (Pteridium aquilinum) extract and bracken spores a number of DNA adducts were detected by P-32-postlabeling. Three of these adducts have been described previously (Povey et al., Br. J.
A S Prakash, A C Povey, P J O'Connor
exaly   +3 more sources

Carcinogenic Effects of Ptaquiloside in Bracken Fern and Related Compounds [PDF]

British Journal of Cancer, 2000
Consumption of the bracken fern Pteridium aquilinum by cattle has been shown to induce bladder and intestinal carcinomas in cattle and to cause a number of diseases in other farm animals. An unstable glucoside named ptaquiloside, containing a reactive cyclopropane ring, has been isolated from the fern and its potent carcinogenicity proven.
M S Baird
exaly   +3 more sources

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Ptaquilosin, the aglycone of a bracken carcinogen ptaquiloside: Chemical derivation from ptaquiloside and the reactivity

Tetrahedron, 1989
Abstract From a bracken carcinogen ptaquiloside (2), the aglycone ptaquilosin (1) has been prepared by a series of chemical reactions. Action of weak base on ptaquilosin (1) caused dehydration to generate the highly reactive dienone (3) the ultimate form of 2.
Hideo Kigoshi, Akihiko Sawada, Yoshifumi Imamura, Haruki Niwa, Kiyoyuki Yamada   +4 more
openaire   +2 more sources

Determination of ptaquiloside in ten species of Pteris in northwestern Argentina

Toxicon, 2023
The toxic effect of ferns of the genus of Pteris in bovines is caused by ptaquiloside, the main carcinogenic toxin. In this study, ten species of Pteris fern in different phenologic stages and plant conditions were collected in northwest Argentina. The phytochemical analysis showed the presence of Pt in the recent collected samples (adults and young ...
Aguirre Castro, Laura Sabrina, Martinez, Olga Gladys, Gardner, Dale R., Barbeito, Claudio Gustavo, Micheloud, Juan Francisco   +4 more
openaire   +3 more sources

Kinetics of ptaquiloside hydrolysis in aqueous solution

Environmental Toxicology and Chemistry, 2006
Abstract Ptaquiloside (PTA) is a well-known toxin produced by the bracken fern (Pteridium aquilinum (L.) Kuhn). It is proposed that PTA from bracken stands can leach through soil and sediments into drinking-water reservoirs, thus representing a concern for human health. To predict the persistence of the toxin, a full understanding of the
Ayala Luis, Karina Barbara, Hansen, Pernille B., Rasmussen, Lars Holm, Hansen, Hans Christian Bruun   +3 more
openaire   +2 more sources

Degradation kinetics of ptaquiloside in soil and soil solution

Environmental Toxicology and Chemistry, 2007
AbstractPtaquiloside (PTA) is a carcinogenic norsesquiterpene glycoside produced in bracken (Pteridium aquilinum (L.) Kuhn), a widespread, aggressive weed. Transfer of PTA to soil and soil solution eventually may contaminate groundwater and surface water.
Ovesen, Rikke Gleerup, Rasmussen, Lars Holm, Hansen, Hans Christian Bruun   +2 more
openaire   +3 more sources

Dennstoside a, an analogue of ptaquiloside, from Dennstaedtia scabra

Phytochemistry, 1991
Abstract A new illudane-type sesquiterpene glycoside, named dennstoside A, was isolated from Dennstaedtia scabra and characterized as an analogue of ptaquiloside, the carcinogenic principle of Pteridium aquilinum, on the basis of spectral analyses and chemical conversion to pterosin A.
Kiyotaka Koyama, Satoshi Takatsuki, Shinsaku Natori   +2 more
openaire   +1 more source

Reproduction of acute bracken poisoning in a calf with ptaquiloside, a bracken constituent

Veterinary Record, 1984
Acute bracken fern toxicity in a calf was reproduced with ptaquiloside, a norsesquiterpene glucoside, isolated from the boiling water extract of bracken fern. Ptaquiloside was dissolved in 500 ml of saline and administered by drench at increasing dosages for six days out of every seven for the following periods: 400 mg/day for 24 days, 800 mg/day for ...
I, Hirono, Y, Kono, K, Takahashi, K, Yamada, H, Niwa, M, Ojika, H, Kigoshi, K, Niiyama, Y, Uosaki   +8 more
openaire   +2 more sources

A New, Very Sensitive Method of Assessment of Ptaquiloside, the Major Bracken Carcinogen in the Milk of Farm Animals

Food Chemistry, 2011
We describe a new method to detect trace levels of ptaquiloside (Pta), a major carcinogen of bracken fern in biological samples such as milk from farm animals.
RUSSO, VALERIA, R. Marabelli, C. Raso, SANTORO, ADRIANO MICHELE LUIGI, F. S. Romolo, F. Bonadies, R. Nicoletti, F. D. Giovanni, G. Berardi, ROPERTO, SANTE, A. Tagarelli, ROPERTO, FRANCO PEPPINO, Russo Valeria, Tagarelli Antonio, Marabelli Romano, De Giovanni Francesco, Nicoletti Rosario, Roperto Sante, Berardi Giorgio, Romolo Francesco Saverio, Bonadies Francesco, Raso Cinzia, Santoro Adriano, Romolo, F., Roperto Franco   +24 more
exaly   +3 more sources

Determination of ptaquiloside in bracken fern (Pteridium esculentum)

Journal of Chromatography A, 1991
Abstract A high-performance liquid chromatography method is described for the analysis of the potent carcinogen, ptaquiloside in bracken fern ( Pteridium esculentum ). The method involves aqueous extraction at room temperature followed by clean-up through a polyamide resin column.
Michael P. Agnew, Dennis R. Lauren
openaire   +1 more source