Results 91 to 100 of about 80,402 (303)

The U1 snRNP protein U1C and Helix H of U1 snRNA are critical for small molecule splicing modulator function

open access: yesNature Communications
Risdiplam and branaplam represent two classes of small-molecule splicing modulators that promote U1 snRNP recognition of weak non-canonical GA/GU-containing 5’ splice sites (ss).
Zhiling Kuang   +15 more
doaj   +1 more source

Advances in MAD-X using PTC [PDF]

open access: yes, 2007
For the last few years the MAD-X program makes use of the Polymorphic Tracking Code (PTC) to perform calculations related to beamdynamics in the nonlinear regime.
E. Forest   +5 more
core   +1 more source

Durable Fuel Cell Cathode Enabled by Pt Embedded Nanoscale Carbon Network via a Scalable Process

open access: yesCarbon Energy, EarlyView.
Platinum nanoparticles embedded nanoscale carbon network (Pt‐e‐Cn) are developed via a scalable flame spray pyrolysis process. Proton exchange membrane fuel cells (PEMFC) employing mesoporous Pt‐e‐Cn cathode electrocatalysts exhibit exceptional durability without compromising performance.
Suriya Venkatesan   +10 more
wiley   +1 more source

CT4/2015: Diagnóstico de visibilidad en carreteras con nubes de puntos obtenidas mediante sistemas LiDAR

open access: yes, 2017
[Resumen]: La metodología presentada se ha probado en ocho casos de estudio; todos ellos correspondientes a zonas de carretera en Galicia, una región en el sudoeste de España, incluyendo un par de casos en entornos urbanos que presentan un comportamiento
Iglesias Valiño, Óscar   +4 more
core  

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

open access: yesChemistry – A European Journal, EarlyView.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang   +10 more
wiley   +1 more source

MAPK13 promotes the progression of papillary thyroid cancer

open access: yesEuropean Thyroid Journal
Objective: This study aims to analyze the genes that influence PTC progression and investigate the role of MAPK13 in PTC. Methods: Differentially expressed genes (DEGs) in Gene Expression Omnibus (GEO): GSE3467, GSE3678, GSE33630, and GSE58545 were ...
Runyu Zhao   +9 more
doaj   +1 more source

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

open access: yesCytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen   +3 more
wiley   +1 more source

Oncolytic Vaccinia Virus-Mediated Antitumor Effect and Cell Proliferation Were Promoted in PTC by Regulating circRNA_103598/miR-23a-3p/IL-6 Axis

open access: yesCancer Management and Research, 2020
Shuilong Zhang,1 Qiang Wang,1 Dewei Li,1 Bo Huang,2 Xia Hou,3 Dongliang Wang,1 Zhifu Xiao,1 Hongjing Meng,1 Yuhang Zhang,1 Lingxiang Dong1 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, People’s Republic of ...
Zhang S   +9 more
doaj  

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