Results 11 to 20 of about 161,469 (302)
A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC [PDF]
, 2015 The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor mediating the toxicity and tumor-promoting properties of dioxin. AHR has been reported to be overexpressed and constitutively active in a variety of solid tumors, but few data
Barollo, Susi +16 more
core +8 more sources
CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]
, 2018 The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro +15 more
core +3 more sources
Health and Quality of Life Outcomes, 2022 Background To describe the reduced health-related quality of life (HRQoL) of duchenne muscular dystrophy (DMD) patients and their caregiver burden and to present its relationship with disease progression.
Valeska Andreozzi +10 more
doaj +1 more source
Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. [PDF]
, 2016 BackgroundWell-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most being papillary thyroid carcinoma (PTC). The objective of the study was to assess the prevalence of different mutations in pediatric WDTC and correlate the ...
Cheng, Shih-Min +9 more
core +1 more source
A deep learning approach to identify gene targets of a therapeutic for human splicing disorders
Nature Communications, 2021 Drugs that modify RNA splicing are promising treatments for many genetic diseases. Here the authors show that deep learning strategies can predict drug targets, strongly supporting the use of in silico approaches to expand the therapeutic potential of ...
Dadi Gao +24 more
doaj +1 more source
High fat diet deviates PtC-specific B1 B cell phagocytosis in obese mice [PDF]
, 2014 Phagocytosis had been attributed predominantly to "professional" phagocytes such as macrophages, which play critical roles in adipose tissue inflammation.
Allaimo, Danielle +8 more
core +1 more source
Frontiers in Oncology, 2022 ObjectiveTo compare the initial success rate, feasibility, and effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) versus percutaneous transhepatic cholangiography (PTC) for anastomotic biliary stricture after liver transplantation (LT)
Hu Bowen +14 more
doaj +1 more source
Investigation of the behavior of a heating system coupled to parabolic trough solar collector system [PDF]
E3S Web of Conferences, 2022 The objective of this work is to study the thermal behavior of a solar heating system using an active layer, integrated in a wall and supplied with hot water by a parabolic trough solar collector (PTC).
Mellaikhafi Abdellah +4 more
doaj +1 more source
International Journal of Sustainable Energy, 2022 Enhancing the thermal efficiency of parabolic solar collectors is still a challenging issue. In this study, two strategies including using nanofluid and a rotary turbulator are applied to ameliorate thermal efficiency.
Peiman Sepahvand +2 more
doaj +1 more source
Thermodynamic evaluation of a novel geothermal and solar-driven multigeneration system for hydrogen and freshwater production [PDF]
Hydrogen, Fuel Cell & Energy Storage, 2023 In this study, a novel multigeneration cycle including PTC and geothermal as the main energy sources and Kalina and ORC cycles as the main power production cycles have been proposed and analyzed from energy and exergy point of view.
Amin Habibzadeh +4 more
doaj +1 more source