Results 11 to 20 of about 80,402 (303)

Improving the Accuracy of Papillary Thyroid Cancer Pathological Evaluation With Digital PCR Detection of the BRAF V600E Mutation. [PDF]

J Clin Lab Anal
This study developed a highly sensitive and specific digital PCR assay for BRAF V600E mutation detection in papillary thyroid cancer (PTC). The increased sensitivity of BRAF mutation detection directly led to more accurate pathological diagnosis of PTC and in turn improved clinical care in patients with limited sample availability or in samples with ...
Yu N, Zhang K, Jiang Y, Zheng L, He X, He Q, Dai M, Hu T, Tang D, Jin J, Huang X, Xiao L.   +11 more
europepmc   +2 more sources

Spatial and single-nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers. [PDF]

Mol Oncol
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Tourneur A, Vitória JR, Saiselet M, Craciun L, Larsimont D, Lefort A, Libert F, Maenhaut C, Costagliola S, Tarabichi M, Romitti M, Detours V.   +11 more
europepmc   +2 more sources

ptc-print

, 2022
Updates Added operator () overload for string initialization:std::string msg = ptc::print( ptc::mode::str, "I am a", "string!" ) Added a corresponding enum class mode to deal with string initialization.
Gianluca, Bianco
core   +1 more source

Quality of life and informal care burden associated with duchenne muscular dystrophy in Portugal: the COIDUCH study

Health and Quality of Life Outcomes, 2022
Background To describe the reduced health-related quality of life (HRQoL) of duchenne muscular dystrophy (DMD) patients and their caregiver burden and to present its relationship with disease progression.
Valeska Andreozzi, Pedro Labisa, Melina Mota, Susana Monteiro, Rita Alves, João Almeida, Björn Vandewalle, Jorge Felix, Katharina Buesch, Hugo Canhão, Igor Beitia Ortiz de Zarate   +10 more
doaj   +1 more source

The reasonable therapeutic modality for biliary duct-to-duct anastomotic stricture after liver transplantation: ERCP or PTC?

Frontiers in Oncology, 2022
ObjectiveTo compare the initial success rate, feasibility, and effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) versus percutaneous transhepatic cholangiography (PTC) for anastomotic biliary stricture after liver transplantation (LT)
Hu Bowen, Hu Bowen, Hu Bowen, Guo Wenzhi, Guo Wenzhi, Guo Wenzhi, Wen Peihao, Wen Peihao, Wen Peihao, Shi Jihua, Shi Jihua, Shi Jihua, Zhang Shuijun, Zhang Shuijun, Zhang Shuijun   +14 more
doaj   +1 more source

A deep learning approach to identify gene targets of a therapeutic for human splicing disorders

Nature Communications, 2021
Drugs that modify RNA splicing are promising treatments for many genetic diseases. Here the authors show that deep learning strategies can predict drug targets, strongly supporting the use of in silico approaches to expand the therapeutic potential of ...
Dadi Gao, Elisabetta Morini, Monica Salani, Aram J. Krauson, Anil Chekuri, Neeraj Sharma, Ashok Ragavendran, Serkan Erdin, Emily M. Logan, Wencheng Li, Amal Dakka, Jana Narasimhan, Xin Zhao, Nikolai Naryshkin, Christopher R. Trotta, Kerstin A. Effenberger, Matthew G. Woll, Vijayalakshmi Gabbeta, Gary Karp, Yong Yu, Graham Johnson, William D. Paquette, Garry R. Cutting, Michael E. Talkowski, Susan A. Slaugenhaupt   +24 more
doaj   +1 more source

Investigation of the behavior of a heating system coupled to parabolic trough solar collector system [PDF]

E3S Web of Conferences, 2022
The objective of this work is to study the thermal behavior of a solar heating system using an active layer, integrated in a wall and supplied with hot water by a parabolic trough solar collector (PTC).
Mellaikhafi Abdellah, Tilioua Amine, Hajjaj Mohamed, Bouaaddi Abella, Messaoudi Choukri   +4 more
doaj   +1 more source

Thermal efficiency enhancement of parabolic trough receivers using synthesized graphene oxide/SiO2 nanofluid and a rotary turbulator

International Journal of Sustainable Energy, 2022
Enhancing the thermal efficiency of parabolic solar collectors is still a challenging issue. In this study, two strategies including using nanofluid and a rotary turbulator are applied to ameliorate thermal efficiency.
Peiman Sepahvand, Faeze Kazemi Andalib, Sahar Noori   +2 more
doaj   +1 more source

Thermodynamic evaluation of a novel geothermal and solar-driven multigeneration system for hydrogen and freshwater production [PDF]

Hydrogen, Fuel Cell & Energy Storage, 2023
In this study, a novel multigeneration cycle including PTC and geothermal as the main energy sources and Kalina and ORC cycles as the main power production cycles have been proposed and analyzed from energy and exergy point of view.
Amin Habibzadeh, Majid Abbasalizadeh, Iraj Mirzaee, samad jafarmadar, Hassan Shirvani   +4 more
doaj   +1 more source

Diagnostic Challenge of Contralateral Intranodal Thyroid Inclusions in a Patient With Synchronous Oropharyngeal and Papillary Thyroid Carcinoma: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Distinguishing benign intranodal thyroid inclusions from metastatic papillary thyroid carcinoma is vital in synchronous malignancies to prevent overstaging. Integrating morphological analysis with BRAF VE1 immunohistochemistry ensures diagnostic precision to align management with the true pathological stage, avoiding unnecessary aggressive ...
Rau BC, Chen YA, Huang CW.
europepmc   +2 more sources