Urinary Tryptophan-Kynurenine Pathway Profiling in Bulgarian Children with Autism Spectrum Disorder (ASD): Neopterin Co-Varies with Kynurenine and Quinolinic Acid. [PDF]
Slavov V +4 more
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DNAJC12 Deficiency, an Emerging Condition Picked Up by Newborn Screening: A Case Illustration and a Novel Variant Identified. [PDF]
Wong TS +11 more
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PredCMB: predicting changes in microbial metabolites based on the gene-metabolite network analysis of shotgun metagenome data. [PDF]
Ji J, Jung S.
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Myoclonus in Pediatric Metabolic Diseases: Clinical Spectrum, Mechanisms, and Treatable Causes-A Systematic Review. [PDF]
Majewska E +3 more
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Follow-up and outcome of patients with primary BH4 deficiencies. [PDF]
Nardecchia F +5 more
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Tetrahydrobiopterin(BH4)cofactor is essential for various enzyme activities, including phenylalanine-4-hydroxylase(PAH), tyrosine-3-hydroxylase(TH), tryptophan-5-hydroxylase(TPH), nitric oxide synthase(NOS), and glyceryl-ether monooxygen-ase(GEMO).The de novo biosynthesis pathway of BH4 from guanosine triphosphate (GTP) involves GTP cyclohydrolase I ...
Blau, N, Thöny, B
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A Prebiotic Synthesis of Pterins
Chemistry - A European Journal, 2015AbstractThe genesis of life on Earth is a hypothesis of evolutionary science that can be, at least partially, tested experimentally. The prebiotic synthesis of cofactors or coenzymes is a poorly explored issue, likely because their formation under plausible prebiotic conditions is not clear.
Marta Ruiz-Bermejo
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Plasma pterins and folate in late life depression: The Rotterdam Study [PDF]
Contains fulltext : 49699.pdf (Publisher’s version ) (Open Access)Tetrahydrobiopterin is a cofactor in the synthesis of monoamine neurotransmitters. High neopterin levels generally signal increased immune activation.
Monique M B Breteler, Amanda J Kiliaan
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Paper Chromatography of Pterins
Nature, 1949THE detection and identification of pterins in small quantities was carried out by Schopf and Becker1 in the course of their classical work on this class of pigments. They employed a chromatographic technique using 0·004 N aqueous hydrochloric acid or 0·01 N methyl alcoholic hydrochloric acid solutions on micro-absorption columns of alumina or ...
P M, GOOD, A W, JOHNSON
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