Results 101 to 110 of about 24,513 (256)

MiR-199a-3p/5p participated in TGF-β and EGF induced EMT by targeting DUSP5/MAP3K11 in pterygium

Journal of Translational Medicine, 2020
Recently, it has been reported that miRNA is involved in pterygium, however the exact underlying mechanism in pterygium is unrevealed and require further investigation.
Siying He, Yifang Huang, Shiqi Dong, Chen Qiao, Guohua Yang, Shuai Zhang, Chen Wang, Yuting Xu, Fang Zheng, M. Yan   +9 more
semanticscholar   +1 more source

Molecular Landscape in Limb Anomalies: Diagnostic Yield and New Candidate Genes

Clinical Genetics, Volume 109, Issue 3, Page 424-436, March 2026.
In 132 individuals with limb anomalies, diagnostic yield was 36% (47/132), including 25 novel variants, three cases with new phenotypes, and two candidate loci, HOXA11 and a small 2q31.1 deletion. Mouse data and exome‐wide analysis, key in identifying the candidate loci, represent an important opportunity for gene discovery.
Akram Mokhtari, Jade Charbonneau, Valancy Miranda, Khadijé Jizi, Marie‐Ange Delrue, Patricia Egerszegi, Isabelle Thiffault, Philippe M. Campeau   +7 more
wiley   +1 more source

The Effects of Job on the Development of Pterygium

Türk Oftalmoloji Dergisi, 2013
Purpose: To investigate the effects of job on the development of pterygium. Material and Method: We retrospectively evaluated the files of 182 patients who were diagnosed as having pterygium between August 2012 and October 2012 in the Ophthalmology ...
Emre Gümüş, İbrahim Yaşar
doaj   +1 more source

Cirrhosis of Liver in Patients With Dyskeratosis Congenita: A Report of Two Cases

Clinical Case Reports, Volume 14, Issue 2, February 2026.
Classical mucocuaneous triad of dyskeratosis congenita in a patient with decompensated cirrhosis. ABSTRACT Dyskeratosis congenita (DC) is a genetic disorder characterized by multisystem involvement. The most commonly affected systems are the mucocutaneous, bone marrow, and lungs.
Bigyan Maharjan, Pradeep Neupane, Bikash Poudel, Ramesh Jha, Suraj Subedi, Jessica Baral, Abhishek Pandit, Shraddha Uprety, Mukesh Kumar Ranjan   +8 more
wiley   +1 more source

PTERYGIUM

The Professional Medical Journal, 2018
Objective: To study the results of primary pterygium excision through bare scleratechnique with and without intraoperative Mitomycin C use. Study design: This was anexperimental study with randomised controlled trial. Setting and Duration: This study wasconducted at Eye A unit, Khyber Teaching Hospital, Peshawar from May,2007 to April,2009.Methodology:
Muhammad Rafiq, Asif Iqbal, Imran Ahmed, Javed Rasul, Muhammad Waseem, Ameer Hamza   +5 more
openaire   +3 more sources

Effect of pterygium excision on pterygium induced astigmatism.

Indian Journal of Ophthalmology, 2003
Pterygium is known to affect refractive astigmatism, which can have a significant impact on vision. This study was undertaken to evaluate the effect of pterygium excision on refractive astigmatism.
Maheshwari Sejal
doaj  

Expression of CD44, PCNA and E-cadherin in pterygium tissues

Indian Journal of Ophthalmology
Purpose: Pterygium is a common ocular surface disease defined by fibrovascular conjunctival growth extending onto the cornea. However, its pathogenesis remains unclear.
Humeyra Yıldırım, Gulay Turan, Meydan Turan   +2 more
doaj   +1 more source

Comparative analysis of histopathological and clinical characteristics of pterygium [PDF]

, 2010
Background/Aim. Pterygium internum presents a significant epidemiological problem. Its etiopathogenesis is still unclear. After surgical removal it shows great tendency to recidives.
Džunić Boban N., Jovanović Predrag, Petrović Aleksandar, Stefanović Ivan, Veselinović Dragan, Zlatanović Gordana   +5 more
core   +1 more source

The in vitro anti-fibrotic effect of Pirfenidone on human pterygium fibroblasts is associated with down-regulation of autocrine TGF-β and MMP-1

International Journal of Medical Sciences, 2020
We aimed to investigate the in vitro effect of pirfenidone (PFD) on proliferation, migration and collagen contraction of human pterygium fibroblasts (HPFs). HPFs were obtained from tissue explants during pterygium surgery.
Yijin Tao, Qin Chen, Can Zhao, Xiao Yang, Qing Cun, Wenyan Yang, Y. Zhang, Ying-Ting Zhu, H. Zhong   +8 more
semanticscholar   +1 more source

Identification of a De Novo MAGEL2 Pathogenic Variant in Schaaf–Yang Syndrome and the Importance of Paternal Allele Confirmation

Journal of Clinical Laboratory Analysis, Volume 40, Issue 3, February 2026.
This study reports a de novo MAGEL2 pathogenic variant in a patient with Schaaf–Yang syndrome, confirmed through methylation‐sensitive analysis. Combining genomic sequencing with methylation assays helps accurately determine the parental origin of MAGEL2 mutations.
Youn‐Ji Hong, Misun Yang, Hyeon Jeong Kwon, Jooyoung Cha, Ja‐Hyun Jang, Sung Eun Wang, Eun Sun Lee, Mi‐Ae Jang   +7 more
wiley   +1 more source