Results 51 to 60 of about 9,548 (210)
Energies, 2018 Accurate parameter identification of pump turbine governing system (PTGS) is of great importance to the precise modeling of pumped storage unit. As PTGS is characterized by uncertainties and strong nonlinear characteristics, it is difficult to identify ...
Jianzhong Zhou +3 more
doaj +1 more source
Structural characterization of PTG and PTG/PP1 protein complex
, 2022 PTG (protein targeting to glycogen) is a scaffolding protein that is involved in the activation of glycogen synthesis by bringing PP1 (type 1 protein phosphatase) to its substrates. It is proposed as a target for the treatment of Lafora disease (LD), a genetic disorder manifested by catastrophic teenage onset of progressive myoclonus epilepsy.
openaire +2 more sources
, 2001 Over the past several years, RNAi and its related phenomena have emerged not only as a powerful experimental tool but also as a new mode of gene regulation.
Bernstein, E. +2 more
core +1 more source
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Advanced Science, EarlyView.Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2003 Specific post-transcriptional gene silencing (PTGS) of target genes can be induced in a variety of organisms by providing homologous double-stranded RNA (dsRNA) molecules. In plants, PTGS is part of a defense mechanism against virus infection.
F. Tenllado +5 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.This study introduces FIRE‐GNN, a force‐informed, relaxed equivariant graph neural network for predicting surface work functions and cleavage energies from slab structures. By incorporating surface‐normal symmetry breaking and machine learning interatomic potential‐derived force information, the approach achieves state‐of‐the‐art accuracy and enables ...
Circe Hsu +5 more
wiley +1 more source
Biotechnology & Biotechnological Equipment, 2019 Post-transcriptional gene silencing is an effective tool for viral replication control at the epigenetic level. In this study, we aimed to produce dsRNAs and siRNA pools targeting the genetic region for the viral protease 3C and the genetic region ...
Nikolay Petrov +2 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundTotal parathyroidectomy (PTx) is often performed to treat secondary hyperparathyroidism (SHPT). Successful PTx is essential to prevent recurrent and persistent SHPT because remnant parathyroid glands (PTGs) in the neck can be stimulated and may
Takahisa Hiramitsu +8 more
doaj +1 more source
Efficient cloning system for construction of gene silencing vectors in Aspergillus niger [PDF]
, 2008 An approach based on Gateway recombination technology to efficiently construct silencing vectors was developed for use in the biotechnologically important fungus Aspergillus niger. The transcription activator of xylanolytic and cellulolytic genes XlnR of
Graaff, L.H., de +3 more
core +2 more sources
Potential Analysis of On‐Site Oxygen and Ozone Production for Wastewater Treatment Plants
Chemie Ingenieur Technik, EarlyView.The potential of a power‐to‐gas process focusing on the oxygen stream to cover an upcoming demand of ozone at German wastewater treatment plants is analyzed. Economic and ecological parameters are compared to the conventional production of hydrogen and oxygen. Powered by on‐site produced wind energy, the process is deemed beneficial.
Vincenta Franßen +3 more
wiley +1 more source