Results 11 to 20 of about 1,282 (161)

Survival and Prognostic Factors of 215 Post-Transplant Lymphoproliferative Disorders After Solid Organ Transplantations in a Finnish Nationwide Population-Based Study Over 30 Years. [PDF]

Hematol Oncol
ABSTRACT Post‐transplant lymphoproliferative disorder (PTLD) is a rare, dreaded complication of organ transplantation with major clinical challenges. We conducted a nationwide population‐based study of all solid organ transplant (SOT) recipients (n = 6555), both adults and children, over a 30‐year period in Finland.
Friman TK, Salmela B, Helanterä I, Åberg F, Jahnukainen T, Halme M, Vaittinen S, Lommi J, Pentikäinen MO, Kovanen PE, Leppä S, Räty R.   +11 more
europepmc   +2 more sources

Posttreatment Lyme disease syndrome and myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review and comparison of pathogenesis

Chronic Diseases and Translational Medicine, 2023
Lyme disease is the most common vector‐borne illness in the United States and has been causing significant morbidity since its discovery in 1977. It is well‐documented that about 10% of patients properly treated with antibiotics never fully recover, but ...
Natalie A. Bai, Christie S. Richardson
doaj   +1 more source

Late-Onset Posttransplant Lymphoproliferative Disorders after Solid Organ Transplantation in Adults: A Case Series and Review of the Literature

Case Reports in Transplantation, 2020
The posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of neoplasms that have wide variety of clinical and histological presentations. The management of PTLDs is challenging due to variety of involvement sites and histological
S. Gandhi, E. Behling, D. Behrens, A. Ferber, R. Schwarting, T. Budak-Alpdogan   +5 more
doaj   +1 more source

Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review

Antibiotics, 2022
Lyme disease and associated co-infections are increasing worldwide and approximately 20% of individuals develop chronic Lyme disease (CLD)/Post-Treatment Lyme Disease Syndrome (PTLDS) despite early antibiotics.
Richard I. Horowitz, Phyllis R. Freeman
doaj   +1 more source

Interferon-gamma blocking as a promising treatment for severe liver dysfunction in secondary hemophagocytic lymphohistiocytosis after liver transplantation. [PDF]

JPGN Rep
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome that can occur after solid organ transplantation but remains underrecognized in this setting. The diagnosis is often delayed due to overlapping clinical manifestations with infection, rejection, or malignancy, and management becomes particularly ...
Chen C, Zhou T, Jin J, Luo Y, Shen L, Xia Q, Qian Y.   +6 more
europepmc   +2 more sources

The Clinical, Symptom, and Quality-of-Life Characterization of a Well-Defined Group of Patients with Posttreatment Lyme Disease Syndrome

Frontiers in Medicine, 2017
BackgroundThe increased incidence and geographic expansion of Lyme disease has made it the most common vector-borne infection in North America. Posttreatment Lyme disease syndrome (PTLDS) represents a subset of patients who remain ill following standard ...
Alison W. Rebman, Kathleen T. Bechtold, Ting Yang, Erica A. Mihm, Mark J. Soloski, Cheryl B. Novak, John N. Aucott   +6 more
doaj   +1 more source

Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatment Lyme Disease Syndromes

mBio, 2022
The annual incidence of Lyme disease, caused by tick-transmitted Borreliella burgdorferi, is estimated to be at least 476,000 cases in the United States and many more worldwide.
Felipe C. Cabello, Monica E. Embers, Stuart A. Newman, Henry P. Godfrey   +3 more
doaj   +1 more source

Polymorphic PTLD [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
Post-transplant lymphoproliferative disorders (PTLDs) are serious, life-threatening complications of transplantation, which represent a heterogeneous group of lymphoproliferative diseases and show a spectrum of clinical, morphologic, and molecular genetic features ranging from reactive polyclonal lesions to frank lymphomas.
openaire   +2 more sources

Management of PTLD After Hematopoietic Stem Cell Transplantation: Immunological Perspectives

Frontiers in Immunology, 2020
Post-transplant lymphoproliferative disorders (PTLDs) are life-threatening complications of iatrogenic immune impairment after allogeneic hematopoietic stem cell transplantation (HSCT).
Francesca Compagno, Sabrina Basso, Sabrina Basso, Arianna Panigari, Jessica Bagnarino, Jessica Bagnarino, Luca Stoppini, Luca Stoppini, Alessandra Maiello, Alessandra Maiello, Tommaso Mina, Paola Zelini, Paola Zelini, Cesare Perotti, Fausto Baldanti, Marco Zecca, Patrizia Comoli, Patrizia Comoli   +17 more
doaj   +1 more source

Protein biomarker profiles in serum and CSF in 158 patients with PTLDS or persistent symptoms after presumed tick-bite exposure compared to those in patients with confirmed acute neuroborreliosis.

PLoS ONE, 2022
BackgroundCurrent diagnostics for patients with lingering symptoms categorized as post-treatment Lyme disease syndrome (PTLDS) have their limitations and may be difficult to interpret.
Kenneth Nilsson, Elisabet Skoog, Marie Edvinsson, Andreas Mårtensson, Björn Olsen   +4 more
doaj   +1 more source