Results 51 to 60 of about 94,667 (206)

Evolutionary radiation of large‐bodied gorgonopsians from the lower Abrahamskraal formation of South Africa

open access: yesThe Anatomical Record, EarlyView.
Abstract The middle Permian represents a critical interval in therapsid evolution, when gorgonopsians emerged as some of the first specialized apex predators within terrestrial ecosystems. Despite their significance, the early diversification of Gorgonopsia in Gondwana remains poorly understood due to scarcity and fragmentary material.
Zanildo Macungo   +5 more
wiley   +1 more source

Differences in the expression of the phosphatase PTP-1B in patients with localized prostate cancer with and without adverse pathological features

open access: yesFrontiers in Oncology
IntroductionPatients with adverse pathological features (APF) at radical prostatectomy (RP) for prostate cancer (PC) are candidates for adjuvant treatment. Clinicians lack reliable markers to predict these APF preoperatively. Protein tyrosine phosphatase
Maria T. Bourlon   +8 more
doaj   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Functional SNP panel for parentage assessment and assignment in worldwide goat breeds

open access: yesGenetics Selection Evolution, 2018
Background International standard panels of single nucleotide polymorphisms (SNPs) have replaced microsatellites in several species for parentage assessment and assignment (PA) purposes. However, such a resource is still lacking in goats. The application
Andrea Talenti   +8 more
doaj   +1 more source

Myocardial perfusion single-photon emission computer tomography and coronary angiography results in patients with different pretest probability of ischemic heart disease

open access: yesТерапевтический архив, 2020
Aim. To study the relationship between pretest probability (PTP) of ischemic heart disease (IHD), calculated according to the recommendations of the European Society of Cardiology (ESC) of 2013 and 2019, with the perfusion of the left ventricle of the ...
A. A. Ansheles   +3 more
doaj   +1 more source

Psychological Treatment for Pediatric Feeding Disorder (PFD) and Avoidant/Restrictive Food Intake Disorder (ARFID)

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To produce a consensus statement on the psychological treatment of feeding/eating aversions seen in pediatric feeding disorder (PFD) and avoidant/restrictive food intake disorder (ARFID), diagnoses that share common symptoms and psychological mechanisms but have historically been addressed separately in the literature. Method To help
Colleen T. Lukens   +12 more
wiley   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration

open access: yesEMBO Molecular Medicine, 2023
Vascular endothelial protein tyrosine phosphatase (VE‐PTP) influences endothelial barrier function by regulating the activation of tyrosine kinase receptor Tie2.
Keisuke Shirakura   +6 more
doaj   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Posterolateral tibial plateau fractures are associated with anterolateral complex injuries of the knee in primary ACL injury

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Posterolateral tibial plateau fractures (PLTFs) have been increasingly studied due to their association with soft tissue injuries around the knee. This prospective study aimed to determine whether the presence of PLTFs is associated with soft tissue injuries around the knee and correlates with an increased preoperative quantitative ...
Lukas Willinger   +5 more
wiley   +1 more source

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