Results 291 to 300 of about 260,236 (367)

Defining terminology and outcome measures for evaluating overdose response technology: An international Delphi study

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Introduction Various novel harm reduction services leverage technology to reduce the rising number of drug poisoning deaths, particularly among those who use drugs alone. There is significant variability in terminology and outcome measures in reporting these interventions, complicating efforts to build a comprehensive knowledge base.
William Rioux   +16 more
wiley   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale   +14 more
wiley   +1 more source

Neuronal complexity tracks changes of epileptic activity and identifies epilepsy patients independent of interictal epileptiform discharges

open access: yesEpilepsia, Volume 66, Issue 3, Page 790-801, March 2025.
Abstract Objective To date, the identification of objective biomarkers of neural epileptic activity (EA) remains challenging. We therefore investigated whether neuronal complexity could serve as an interictal electroencephalographic measure of EA, independent of interictal epileptiform discharges (IEDs). By tapering anti‐seizure medication (ASM) during
Ricardo Kienitz   +6 more
wiley   +1 more source

Neurobehavioral therapy in functional seizures: Investigation of mechanism of action with resting‐state functional magnetic resonance imaging

open access: yesEpilepsia, EarlyView.
Abstract Objective Functional seizures (FS) often disrupt the key regions integral to cognitive processing and emotional regulation (anterior insula, anterior cingulate, and temporoparietal junction). We investigated the potential neurophysiologic mechanism of action (MOA) of neurobehavioral therapy (NBT) using resting‐state functional MRI seed‐based ...
Jerzy P. Szaflarski   +8 more
wiley   +1 more source

A multidisciplinary look into transgender and gender diverse people with epilepsy: An at‐risk and underreported population

open access: yesEpilepsia, EarlyView.
Abstract The literature describing transgender (TG) and gender‐diverse (GD) people with epilepsy (PWE) is sparse. Gender‐affirming care (GAC) can impact epilepsy management due to interactions with anti‐seizure medications (ASMs) and the potential effects on seizure control.
MarieElena Byrnes   +4 more
wiley   +1 more source

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