Results 191 to 200 of about 31,132 (258)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

From classic to cutting-edge: technological approaches to respiratory physiological signals in assessing sleep-disordered breathing. [PDF]

J Clin Sleep Med
Chiang AA, Lee-Iannotti J, Torstrick B, Berry RB, Collop NA.   +4 more
europepmc   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Augmentation for rotator cuff repair - clinical use patterns and limited patient access: the American Shoulder and Elbow Surgeons bio-advocacy work group survey. [PDF]

JSES Rev Rep Tech
Bushnell BD, Boes N, Cil A, Farmer K, Gilot G, Kassam H, Khan A, Miniaci A, Port J, Sanchez-Sotelo J, Schultzel M, Steinmann S, Suri M, Weinstein D, Wright M.   +14 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

2D MoS₂-conformal 3D-printed platform for dual-phototherapy and bone regeneration. [PDF]

Nano Converg
Seo JH, Choi I, Lee H, Bang S, Kang HS, Moon CH, Gwon JY, Lee N, Kim G, Cho YH, Choi S, Joo H, Kim JH, Song E, Kim J, Kim D, Kang S, Lee DY, Lim D, Yang K, Cha GD, Lee SH, Park J, Kang MH, Jung HD.   +24 more
europepmc   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, Volume 13, Issue 36, 29 June 2026.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Gyrosphygmogram-Based Blood Pressure Estimation: A Comparative Study of Pulse Transit Time and CNN-LSTM Methods. [PDF]

IEEE Open J Eng Med Biol
Yaghoobi N, Sethi R, Huisman E, Fung K, Park EJ.   +4 more
europepmc   +1 more source

Curcumin-functionalized Prussian blue for NIR-II photothermal antibacterial therapy. [PDF]

Discov Nano
Li Z, Sun G, Ge F, Shen Y, Yang X, Yao B, Yu C, Su S, Yao J, Wang Y.   +9 more
europepmc   +1 more source

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To bleed or not to bleed? is that the question for the PTT?

Journal of Thrombosis and Haemostasis, 2005
The activated partial thromboplastin time (PTT) is the grandchild of the Lee-White whole blood clot time (WBCT). Both tests were developed to assist the diagnostic process for patients who exhibited features consistent with hemophilia, i.e., the pretest probability was extremely high. Probably
openaire   +2 more sources