Results 41 to 50 of about 40,418 (310)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

WORKING AND LEGAL POSITION OF THE EMPLOYEES OF THE INSOLVENT DEBTOR AND CLAIMS OF THE EMPLOYEES IN THE CASE OF INSLOLVENCY PROCEEDINGDS OF THE EMPLOYER, LEGAL REGULATIONS AND REALITY

Pravo, 2012
In Serbia, the Insolvency Law has been applied since 24th January 2010 (The Public Herald of Republic of Serbia no. 104/09). There have been great expectations of the Insolvency Law since the day it was issued.
Vesna Bilbija
doaj  

Innovative strategies to boost photothermal therapy at mild temperature mediated by functional nanomaterials

Materials & Design, 2022
The last few years have witnessed explosive growth in the design and development of various photothermal agents (PTAs) to realize phtothermal therapy (PTT) for eradicating solid tumors. Nevertheless, the therapeutic efficacy of PTT is still restricted by
Yuanyuan Cao, Quanzhong Ren, Rongzhang Hao, Zhiwei Sun   +3 more
doaj   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Application of Recombinant VII Activated Coagulation Factor for Children with Resistant Coagulopathy Caused Sepsis

Медицинский вестник Юга России, 2010
Purpose: To investigate the effectiveness of recombinant VII activated coagulation factor in complex therapy of children with resistant coagulopathy caused by sepsis. Materials and Methods: 38 children from 2 months to 17 years old were investigated with
N. Bgane, A. Trembach
doaj  

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Benefits and Value of Big Trees in Urban Area: A Study in Bang Kachao Green Space, Thailand

Environment and Natural Resources Journal, 2018
Green Space is very important for the conservation of biodiversity in the urban areas of Thailand. In the case of Bang Kachao, Green Space has been improved by the development of gardens in the city.
Teeka Yotapakdee, Lamthai Asanok, Torlarp Kamyo, Monton Norsangsri, Napak Karnasuta, Suwit Navakam, Chidchai Kaewborisut   +6 more
doaj   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source