Results 121 to 130 of about 27,465 (240)

Up to Four‐Year Outcomes of Single‐Fraction Stereotactic Radiosurgery for Small Brain Metastases: A Competing‐Risk Analysis

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Introduction Single‐fraction stereotactic radiosurgery (SRS) is recommended for small brain metastases (< 2 cm). However, long‐term outcomes accounting for competing risks—particularly death, which precludes observation of local treatment failure (LTF)—remain limited. Methods We retrospectively analyzed cumulative incidences of LTF, defined as
Isabella Gruber, Oliver Koelbl
wiley   +1 more source

Upper Versus Middle‐Neck Involvement in TNM‐9 Stage IB Nasopharyngeal Carcinoma: Implications for De‐Escalation and Intensification Strategies

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background TNM‐9 Stage IB nasopharyngeal carcinoma (NPC) encompasses markedly heterogeneous risk profiles, yet lacks reliable biomarkers to guide the choice between de‐escalation and intensification strategies. This study aimed to explore the prognostic significance of upper‐ and middle‐neck nodal involvement (UNI and MNI) in this population ...
Hanchuan Xu, Xinlan Chen, Daqiang Huang, Zhiwei Yan, Jingyu Zhu, Lili Zhu, Yahan Zheng, Ziyi Wu, Caizhu Pan, Jing Zhong, Jianji Pan, Shaojun Lin, Junxin Wu, Qiaojuan Guo   +13 more
wiley   +1 more source

Daily adaptive radiotherapy in head and neck squamous cell carcinoma can negatively impact organ at risk dosimetry. [PDF]

Clin Transl Radiat Oncol
Enocson H, Haraldsson A, Engström P, Ceberg S, Gebre-Medhin M, Adrian G, Af Rosenschöld PM.   +6 more
europepmc   +1 more source

Sequential High‐Dose Ruxolitinib and Low‐Dose Splenic Irradiation for Pretransplant Management of Splenomegaly Before Allogeneic Hematopoietic Cell Transplantation With Fludarabine/Busulfan‐Based Conditioning in Myelofibrosis

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Significant splenomegaly remains a major barrier to successful allogeneic hematopoietic cell transplantation (allo‐HCT) in myelofibrosis (MF), contributing to delayed engraftment and an increased risk of graft failure. Systemic JAK inhibition and splenic irradiation are commonly used as independent pretransplant strategies; however,
Peng Ke, Chun Feng, Guoqiang Li, Xiaoyong Chen, Yixuan Cao, Lina Hu, Jiahe Zhang, Linlin Wang, Jihao Zhou   +8 more
wiley   +1 more source

Photon-counting detector computing tomography in treatment planning of head-and-neck cancer. [PDF]

Phys Imaging Radiat Oncol
Lamaj E, Wohlfahrt P, Wilke L, Alkadhi H, Bertini N, Gabrys H, Guckenberger M, Balermpas P, Tanadini-Lang S, Psoroulas S.   +9 more
europepmc   +1 more source

Tumor Growth Rate in Head and Neck Squamous Cell Carcinoma: A Scoping Review

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Objective This scoping review evaluates the current literature on tumor growth rate in head and neck cancer patients and its potential prognostic value on survival, loco‐regional control and recurrence (PROSPERO registration CRD42022370828). Review Methods PubMed, Embase, and Scopus were searched for publications between 1990 and November 5th ...
Gilles Delahaut, Florent Jamme, Bruno Krug, Jean‐François Daisne, Samantha Hassid, Sebastien Van der Vorst   +5 more
wiley   +1 more source

Postoperative fractionated stereotactic radiotherapy for completely resected brain metastases with 25 Gy in five fractions: A single-center retrospective study. [PDF]

Clin Transl Radiat Oncol
Maier SH, Nitschmann A, Dehelean DC, Horne L, Baumgartner C, Anagnostatou V, Garny S, Fleischmann DF, Pazos M, Stoecklein VM, von Baumgarten L, Thon N, Ringel F, Belka C, Corradini S, Marschner SN, Niyazi M, Bodensohn R, Schönecker S.   +18 more
europepmc   +1 more source

Precision Stereotactic Body Radiotherapy for Ultra‐Central NSCLC: Tailored Margins Reduce Toxicity Without Compromising Tumor Control

MedComm, Volume 7, Issue 8, August 2026.
A tailored non‐uniform PTV strategy (including PTVcrop and PTV_high/PTV_low) was used in SBRT for ultra‐central NSCLC to meet stringent OAR constraints. Notably, this SBRT strategy achieved favorable clinical outcomes, with an 84.6% 3‐year local control rate, a median PFS of 42.9 months. Additionally, treatment‐related toxicity was mild, with only 1.5%
Di Liu, Shuangyan Yang, Yun Chen, Ming Liu, Ruifeng Zhao, Minren Hu, Bin Su, QiongYa Wu, Hongyu Wu, Hui Liu, Jinming Yu, Yaping Xu   +11 more
wiley   +1 more source

PCA-based respiratory motion modeling for individualized PTV margin optimization in NSCLC radiotherapy. [PDF]

J Appl Clin Med Phys
Quang HD, Thanh CN, Kieu THT, Van TC.
europepmc   +1 more source

Rare Biallelic CTU2 Variants in an Individual With CAKUT: Clinical Characterization and Minigene Splicing Analysis

Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
Exome sequencing in 200 CAKUT patients identified compound heterozygous rare CTU2 variants in one renal‐predominant case. Minigene splicing assays showed c.913C>T partially increased exon 9 skipping, supporting further case collection and kidney‐relevant studies to clarify the role of CTU2 in renal developmental phenotypes.
Qian Liu, Xueqin Cheng, Bixia Zheng, Chunli Wang, Wei Zhou, Aihua Zhang   +5 more
wiley   +1 more source