Results 161 to 170 of about 36,554 (269)

Toward universal dose prediction: A multi‐scale, multi‐objective framework for sequential boost radiotherapy

Medical Physics, Volume 53, Issue 6, June 2026.
Abstract Background Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occur primarily in the initial plan, the boost plan(s), or all plans, resulting in a time‐intensive, iterative optimization process.
Austen Matthew Maniscalco, Xinran Zhong, Sean Domal, Yu‐Chen Lin, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +7 more
wiley   +1 more source

Fractional flow reserve versus intravascular ultrasound guidance for percutaneous coronary intervention in intermediate coronary stenoses: A systematic review and meta‐analysis

Precision Medical Sciences, Volume 15, Issue 2, Page 102-112, June 2026.
Fractional Flow Reserve versus Intravascular Ultrasound for guiding percutaneous coronary intervention in coronary artery disease: A systematic review and meta‐analysis of 5 studies (over 3,900 patients) showing comparable outcomes in MACE, mortality, and target vessel revascularization.
Sanket Patel, Mirza Muhammad Hadeed Khawar, Mehwish Safdar, Iman Ahsan, Rahul Kumar, Promise Ebube Mbala, Mustafa Abrar Zaman, Salma Frindou, Sabahat Kanwal, Mohammad Issa Ayash, Thomas Viji Pulickal, Sonika Gopathoti, Sai Erambalur, Lima Dalil   +13 more
wiley   +1 more source

Neoadjuvant versus adjuvant chemoradiotherapy for resectable cT3‐4a esophageal squamous cell carcinoma: A matched cohort analysis

Precision Radiation Oncology, Volume 10, Issue 2, Page 155-164, June 2026.
Neoadjuvant chemoradiotherapy (NCRT) significantly improves overall survival over adjuvant chemoradiotherapy for resectable cT3‐4a esophageal squamous cell carcinoma, with comparable progression‐free survival and toxicity. This propensity‐matched study supports NCRT as the preferred strategy for this high‐risk population.
Mingqiang Lin, Yilin Yu, Yibing Hu, Rong Zheng, Jiancheng Li, Qiwei Yao   +5 more
wiley   +1 more source

Impact of Intraprostatic Simultaneous Integrated Boost on Long‐Term Outcomes in Unfavorable Intermediate‐Risk Prostate Cancer Treated With Dose‐Escalated Radiotherapy and Short‐Term Androgen Deprivation Therapy

The Prostate, Volume 86, Issue 8, Page 961-969, June 2026.
ABSTRACT Background Unfavorable intermediate‐risk prostate cancer (UIR‐PCa) represents a biologically heterogeneous subgroup with a higher risk of recurrence compared with favorable intermediate‐risk disease. Contemporary management frequently includes dose‐escalated radiotherapy (RT) combined with short‐term androgen deprivation therapy (ADT). Whether
Cem Onal, Aysenur Elmali, Birhan Demirhan, Ertugrul Senturk, Petek Erpolat, Ozan Cem Guler   +5 more
wiley   +1 more source

Hairy, hairy quite contrary: Pollination and functional floral traits in a hirsute carrion‐scented stapeliad

TAXON, Volume 75, Issue 3, June 2026.
Abstract Floral mimicry of decaying substrates of animal origin, such as carrion or faeces, is associated with unusual traits such as geoflory, deep maroon or yellow colouration, floral hairs and unpleasant odour, but the functional significance of these traits for attracting and manipulating pollinators has seldom been examined.
Adam Shuttleworth, Marc du Plessis, Peter V. Bruyns, Steven D. Johnson   +3 more
wiley   +1 more source

Management of Adult Patients With Isocitrate Dehydrogenase‐Mutant Gliomas in Australia: An Expert Position Statement From the Cooperative Trials Group for Neuro‐Oncology

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 392-403, June 2026.
Following maximal surgery when feasible, management of adult patients with isocitrate dehydrogenase (IDH)‐mutant glioma is complex and should be considered in a neuro‐oncology multidisciplinary context balancing disease control versus potential treatment‐associated toxicities. Options include continued surveillance, radiation therapy, chemotherapy, and/
Mark B. Pinkham, Hao‐Wen Sim, Rosalind L. Jeffree, Arian Lasocki, Dianne M. Legge, Frank Saran, Laveniya Satgunaseelan, Hui K. Gan   +7 more
wiley   +1 more source

Checkpoint inhibitors, obinutuzumab plus PET‐adapted ultra‐low dose nodal radiotherapy yield high efficacy in treatment‐naïve follicular lymphoma: Results from the phase II ‘FLUORO’ study

British Journal of Haematology, Volume 208, Issue 6, Page 2026-2035, June 2026.
Summary Follicular lymphoma (FL) first‐line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment‐naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combination checkpoint inhibition (atezolizumab) and obinutuzumab (6 cycles) with positron emission tomography (PET)
Arina Martynchyk, Geoffrey Chong, Richard Khor, Denise Lee, Sze Ting Lee, Andrew M. Scott, Anneke C. Grobler, Belinda A. Campbell, Thanuja Thachil, Kate Manos, Genevieve Douglas, Alexandra Romano, Jodie B. Palmer, Melinda Burgess, Colm Keane, Eliza A. Hawkes   +15 more
wiley   +1 more source

Functional Data Strengthen Clinical Validation of PhenoScore Phenotype‐Guided AI for ANKRD11 Missense Variants

Clinical Genetics, Volume 109, Issue 6, Page 1038-1048, June 2026.
PhenoScore, an AI framework integrating facial recognition and clinical phenotype data, accurately identifies pathogenic ANKRD11 missense variants associated with KBG syndrome (AUC 0.95). Validated against functional data, PhenoScore outperforms REVEL and complements AlphaMissense, providing objective phenotypic evidence to reduce variants of uncertain
Evi Andriessen, Elke de Boer, Gholson J. Lyon, Bert B. A. de Vries, Charlotte W. Ockeloen, Alexander J. M. Dingemans   +5 more
wiley   +1 more source

Resolved HBV Infection Is Not Associated With Liver‐Related Outcomes in Survival Analysis of Caucasians After HCV Cure

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background Previous exposure to hepatitis B virus (HBV) may influence the risk of developing hepatocellular carcinoma (HCC) and other liver‐related events (LRE), in particular in patients after HCV cure. Previous studies were not conclusive and there are only few large studies on this topic from Europe. Methods We analysed clinical endpoints (≥
Laura Muana Wilhelm, Albrecht Stoehr, Peter Buggisch, Christine John, Ralph Link, Hartwig Klinker, Uta Merle, Markus Cornberg, Christoph Sarrazin, Thomas Berg, Heiner Wedemeyer   +10 more
wiley   +1 more source

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 229-239, June 2026.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai, Michael S. Kent, Michael W. Nolan, Dah‐Renn Fu, Jayme S. Looper   +4 more
wiley   +1 more source