Results 171 to 180 of about 10,062 (208)
Some of the next articles are maybe not open access.
Pentraxins: CRP and PTX3 and Cardiovascular Disease
Inflammation & Allergy - Drug Targets, 2011The pentraxins, C-reactive protein (CRP), serum amyloid P (SAP) and pentraxin3 (PTX3) are useful biomarkers for cardiovascular disease (CVD), particularly ischemic heart disease and heart failure, and are deeply involved in the pathogenesis of CVD linked to inflammation and innate immunity.
Yuichiro, Maekawa +2 more
openaire +2 more sources
The long pentraxin PTX3 in vascular pathology
Vascular Pharmacology, 2006Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cyclic multimeric structure. Based on the primary structure of the subunit, the pentraxins are divided into two groups: short pentraxins and long pentraxins.
A. Mantovani +6 more
openaire +2 more sources
PTX3 as a paradigm for the interaction of pentraxins with the Complement system [PDF]
Seminars in Immunology, 2013 Pentraxins are highly conserved components of the humoral arm of innate immunity. They include the short pentraxins C reactive protein (CRP) and serum amyloid P component (SAP), and the long pentraxin PTX3. These are soluble pattern-recognition molecules that are present in the blood and body fluids, and share the ability to recognize pathogens and ...
Alberto Mantovani +2 more
exaly +4 more sources
Pentraxins in innate immunity: lessons from PTX3
Cell and Tissue Research, 2010The innate immune system constitutes the first line of defence against microorganisms and plays a primordial role in the activation and regulation of adaptive immunity. The innate immune system is composed of a cellular arm and a humoral arm. Components of the humoral arm include members of the complement cascade and soluble pattern recognition ...
Deban L +4 more
openaire +2 more sources
Modulation of diabetes-related retinal pathophysiology by PTX3 [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaDiabetic retinopathy (DR) is a common complication of diabetes characterized by vascular pathology and neuroinflammation. Pentraxin 3 (PTX3) is a soluble pattern recognition molecule that functions at the crossroads between innate immunity, inflammation, and tissue remodeling.
Antonio Inforzato +2 more
exaly +4 more sources
Follicular Fuid Levels of the Long Pentraxin PTX3
Journal of the Society for Gynecologic Investigation, 2006Pentraxin-3 (PTX3) is a long pentraxin that plays a key role in female fertility as a structural and essential constituent of the cumulus oophorus extracellular matrix. Despite considerable evidence supporting this role of PTX3 in mice, data in humans are scanty. The aim of the present study was (1) to evaluate follicular fluid concentrations of PTX3; (
A. Paffoni +8 more
openaire +2 more sources
Role of PTX3 in pancreatic cancer
The Lancet, 2014Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a disease with dismal prognosis and is invariably diagnosed late. Tests used to diagnose or monitor the disease are invasive, inaccurate, and expensive. Tumour-supportive stroma is an important feature of PDAC. All-trans retinoic acid renders activated stellate cells quiescent and thereby
Jennifer Watt +5 more
openaire +1 more source
PTX3: the ensemble biomarker of human diseases
La Rivista Italiana della Medicina di Laboratorio, 2022Palumbo, Valeria +4 more
openaire +3 more sources
PTX3 Deficiency and Aspergillosis
New England Journal of Medicine, 2014Boer, M.G.J. de +2 more
openaire +6 more sources
PTX3 gene expression in Castleman'sdisease
European Journal of Haematology, 2000MALAGUARNERA, Lucia +5 more
openaire +2 more sources