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Serum Dehydroepiandrosterone Sulfate Levels and Pubarche in Short Children Born Small for Gestational Age before and during Growth Hormone Treatment [PDF]
It has been suggested that the programming of the endocrine axes occurs during critical phases of fetal development and will be affected by intrauterine growth retardation.
Paul Mulder +2 more
exaly +3 more sources
The prevalence and risk factors of premature thelarche and pubarche in 4- to 8-year-old girls
Aim: To assess the prevalence of premature thelarche (PT) and pubarche in healthy 4- to 8-year-old girls and to investigate factors associated with early pubertal development.
Zeynep Atay +2 more
exaly +2 more sources
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Premature Pubarche: Time to Revise the Diagnostic Approach?
Premature pubarche (PP) could represent the first manifestation of non-classic congenital adrenal hyperplasia caused by 21 hydroxylase deficiency (NC21OHD) (10–30% of cases).
Rita Ortolano +2 more
exaly +2 more sources
Isolated precocious pubarche: an approach.
The Journal of Clinical Endocrinology & Metabolism, 1994Precocious pubarche (PP) is most often a benign condition secondary to the early appearance of adrenarche. However, PP may be a manifestation of nonclassical adrenal hyperplasia. The incidence of nonclassical adrenal hyperplasia in patients with PP ranges from about 0-40% of cases. Controversy exists as to whether all children with PP should undergo an
BALDUCCI R +4 more
openaire +4 more sources
Premature pubarche: etiological heterogeneity
Journal of Clinical Endocrinology & Metabolism, 1992Premature pubarche is characterized by pubic hair, adult type body odor, acne, and axillary hair before 8 yr of age in girls and 9.5 yr of age in boys. Causes of this premature virilization include premature adrenarche, mild errors of steroidogenesis, precocious puberty, and adrenal and gonadal tumors.
S F, Siegel +4 more
openaire +3 more sources
Genetic Defects of Steroidogenesis in Premature Pubarche*
The Journal of Clinical Endocrinology & Metabolism, 1987Twenty three patients (19 girls, 4 boys) presented with typical features of premature pubarche between the ages of 2-7 yr. The patients were studied for the presence of an adrenal steroidogenic defect by ACTH stimulation testing (Cortrosyn, 0.25 mg iv bolus dose).
J W, Temeck +3 more
openaire +2 more sources
Pronounced Adrenarche and Precocious Pubarche in Boys
Hormone Research in Paediatrics, 1999In girls, pronounced adrenarche with precocious pubarche (PP) has been related to reduced fetal growth and to a cluster of endocrine-metabolic abnormalities. We examined whether these associations are also evident in boys with PP. The study population consisted of matched groups of boys (n = 58; age range 5–15 years) without or with a history of PP ...
N, Potau +4 more
openaire +2 more sources
Premature Pubarche in Children with Pompe Disease
The Journal of Pediatrics, 2015Pompe disease (PD), or glycogen storage disease type II, results from deficiency of acid α-glucosidase. Patients with infantile-onset PD die by early childhood if untreated. Patient survival has improved with enzyme replacement therapy. We report a case series of 8 patients with infantile-onset PD on enzyme replacement therapy with premature pubarche.
Queenie K-G, Tan +8 more
openaire +2 more sources
Natural history of premature pubarche: an auxological study
Journal of Clinical Endocrinology & Metabolism, 1992The natural history of girls with premature pubarche is reported to be normal, but the effects on puberty and on final height are not well documented. We assessed the outcome of a group of girls with premature pubarche from two Latin populations in whom 21-hydroxylase deficiency had been ruled out by an ACTH test.
L. Ibanez +8 more
openaire +4 more sources

