Results 71 to 80 of about 2,122 (197)

Bifocal β‐hCG‐secreting CNS Germinoma in a 13‐Year‐Old Boy: Clinical–Biochemical Pubertal Discordance and Long‐Term Outcome

Case Reports in Pediatrics, Volume 2025, Issue 1, 2025.
Background Intracranial germ cell tumors (GCTs) are rare in the pediatric population. They are classified as germinoma and nongerminomatous and may secrete specific proteins such as β subunit of human chorionic gonadotropin (β‐hCG) and alpha‐fetoprotein (AFP).
Corina Ramona Nicolescu, Sandrine Thouvenin Doulet, Lucie Bazus, Jean-Louis Stephan, Nikhat Kaura   +4 more
wiley   +1 more source

Low DHEAS Concentration in a Girl Presenting with Short Stature and Premature Pubarche: A Novel PAPSS2 Gene Mutation

, 2020
Objective: Dehydroepiandrosterone (DHEA) sulfotransferase (SULT2A1) converts DHEA to DHEA sulfate (DHEAS) which prevents bioactive androgen excess. This enzymatic reaction requires PAPS (3 '-phospho-adenosine-5 '-phosphosulfate) biosynthesis ...
KIRKGÖZ, TARIK, BEREKET, ABDULLAH, ELTAN, MEHMET, KAYGUSUZ, SARE BETÜL, DEMİRCİOĞLU, SERAP, GÜRAN, TÜLAY   +5 more
core   +1 more source

Medical semiology of patients with monogenic obesity: A systematic review

Obesity Reviews, Volume 25, Issue 10, October 2024.
Summary Patients with monogenic obesity display numerous medical features on top of hyperphagic obesity, but no study to date has provided an exhaustive description of their semiology. Two reviewers independently conducted a systematic review of MEDLINE, Embase, and Web of Science Core Collection databases from inception to January 2022 to identify ...
Emeline Renard, Ariane Thevenard‐Berger, David Meyre   +2 more
wiley   +1 more source

Very premature pubarche in girls is not a pubertal variant

Hormones, 2012
Premature pubarche (PP) in girls is considered to be a benign phenomenon and is the clinical expression of premature adrenarche. Since it does not usually increase the risk of either abnormalities in pubertal development or a reduced final adult height, a non-interventional approach is generally adopted after exclusion of non-classical (NC)congenital ...
Françoise, Paris, Nicolas, Kalfa, Pascal, Philibert, Claire, Jeandel, Laura, Gaspari, Charles, Sultan   +5 more
openaire   +2 more sources

High urinary phthalate concentration associated with delayed pubarche in girls

, 2012
Phthalates are a group of chemicals present in numerous consumer products. They have anti-androgenic properties in experimental studies and are suspected to be involved in human male reproductive health problems.
Frederiksen, H, Mouritsen, A, Skakkebaek, N E, Petersen, Jørgen Holm, Hagen, Casper, Sørensen, K, Aksglaede, L, Juul, A, Andersson, Anna-Maria   +8 more
core   +1 more source

Practical approach of precocious pubarche

, 2009
La pubarquia precoz, es considerada una variante normal del desarrollo, sin consecuencias a largo plazo. Recientemente se ha relacionado con alteraciones endocrino-metabólicas en la pre-pubertad y fundamentalmente en la post-pubertad. La pubarquia precoz,
Licha, Minerva
core  

Puberdade precoce: a experiência de um ambulatório de Ginecologia Infanto-Puberal Precocious puberty: the experience of o Pediatric and Adolescent Gynecology Clinic

Revista Brasileira de Ginecologia e Obstetrícia, 2007
OBJETIVO: avaliar os casos com suspeita de puberdade precoce, em relação à classificação diagnóstica e etiológica, atendidos no período compreendido entre os anos de 2000 e 2005.
Márcia Neves de Carvalho, Marcos Felipe Silva de Sá, Ana Carolina Japur de Sá Rosa e Silva, Areana Diogo Nascimento, Flávia Raquel Rosa Junqueira, Rosana Maria dos Reis   +5 more
doaj   +1 more source

Sonography of abdominal organs in precocious puberty in girls

Journal of Ultrasonography, 2013
Precocious puberty constitutes a significant clinical problem due to psychological implications and health concerns as well as consequences associated with girls’ fertility.
Maciej Mazgaj
doaj  

Prevalence of Nonclassic Congenital Adrenal Hyperplasia in Turkish Children Presenting with Premature Pubarche, Hirsutism, or Oligomenorrhoea [PDF]

, 2014
Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder.
Zafer Yuksel, Enver Simsek, Ozden Kutlay, Cigdem Binay, Oguz Cilingir, Sevilhan Artan   +5 more
core   +1 more source

NON CLASSIC 21 HYDROXYLASE DEFICIENT ADRENAL HYPERPLASIA IN PATIENTS WITH ISOLATED PRECOCIOUS PUBARCHE [PDF]

Acta Medica Iranica, 2003
Precocious Pubarche (PP) is most often a benign condition secondary to the early appearance of adrenarche. However, PP may be a manifestation of mild errors of steroidogenesis in particular non classic 21 hydroxylase deficiency (NC210HD).
H. Moayeri, A. Rabbani   +1 more
doaj   +1 more source