Results 201 to 210 of about 1,980,181 (285)

The Association Between Early Sport Specialization and Injury and Career Outcomes Among National Football League Athletes

European Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT Early sport specialization during adolescence has been linked to overuse injuries in several sports, yet its long‐term impact in American football remains underexplored. The purpose of this study is to examine whether early specialization in football during high school is associated with higher injury rates and shorter careers than multi‐sport
Gnaneswar Chundi, Abhiram Dawar, Zachary Fuller, Tuckerman Jones, Shriyaus Lingam, Balazs Galdi   +5 more
wiley   +1 more source

Absence of Testes at Puberty Impacts Functional Development of Nigrostriatal But Not Mesoaccumbal Dopamine Terminals in a Wild-Derived Mouse. [PDF]

eNeuro
Jackson S, Mun J, Prounis G, Phumsatitpong C, Motahari N, Kriegsfeld L, Landry MP, Wilbrecht L.   +7 more
europepmc   +1 more source

A Systematic Evaluation of the Performance of Multiple Brain Age Algorithms in Two Cohorts of Youth

Human Brain Mapping, Volume 47, Issue 2, February 1, 2026.
Performance of five influential brain age estimation algorithms in two population‐based cohorts of youth. Brain age was quantified using estimates of brain structure, and performance was evaluated based on correlations with chronological age, error indices, sensitivity to demographic characteristics, scanning parameters, genetic similarity, and ...
Cleanthis Michael, Natasha S. Jones, Jamie L. Hanson, Heidi B. Westerman, Kelly L. Klump, Colter Mitchell, Christopher S. Monk, S. Alexandra Burt, Luke W. Hyde   +8 more
wiley   +1 more source

Brief Report: Is Gestational Exposure to HIV and Protease Inhibitors Associated With Timing of Pubertal Onset? [PDF]

J Acquir Immune Defic Syndr
Serghides L, Lee J, Jacobson DL, Geffner ME, DiMeglio LA, McFarland EJ, Powis KM, Williams PL, Jao J, Pediatric HIV/AIDS Cohort Study.   +9 more
europepmc   +1 more source

Development of Pediatric Dosing for Mepolizumab in Severe Asthma Based on Extrapolation of Data From Adult Patients and a Phase II Open‐Label Pediatric Trial

The Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract The benefit–risk profile of mepolizumab in severe asthma was established through clinical trials in adults, leading to EU and US approvals in 2015. To support a pediatric indication (≥6 years), an extrapolation approach was implemented. This extrapolation and its validation were informed by data from Phase III trials in adults (N = 1841) and ...
Atul Gupta, Isabelle J. Pouliquen, Wanda Phipatanakul, Daren Austin, Glenn Whelan, Robert G. Price, Tricia Finney‐Hayward, Sabine Derey, Jonathan Steinfeld   +8 more
wiley   +1 more source

Clinical practice guidelines for the management of differences of sex development in Japan. [PDF]

Clin Pediatr Endocrinol
Ishii T, Kashimada K, Kawai M, Itonaga T, Iwasa T, Utsunomiya A, Ozaki K, Kawamura K, Kanno J, Koh J, Kojima Y, Sasaki S, Sato H, Shiraishi K, Naiki Y, Nishiyama M, Hamajima T, Fujisawa Y, Makita N, Matsui K, Yanai T, Horikawa R, Ogata T.   +22 more
europepmc   +2 more sources

The Ontogenetic Development of Rapid Eye Movement Sleep in Early Life and Its Regulatory Mechanisms

International Journal of Developmental Neuroscience, Volume 86, Issue 1, February 2026.
REM sleep was first identified in humans and cats in the late 1950s and exhibits a conserved developmental trajectory across species. This study elucidates key characteristic changes during REM sleep development, thereby providing a foundation for improving the prevention and treatment of various neurodevelopmental disorders.
Xiu‐Juan Zhang, Xu‐Hao Gao, An‐Hong Wang, Cai‐Qin Wang, Jia Liu, Yan‐Li Hu, Bo‐Wen Duan, Hai‐Yun Huang, Jin‐Xian Gao   +8 more
wiley   +1 more source

Clinical Presentation and Management of Swyer Syndrome: A Case Report. [PDF]

Cureus
Errahali Y, Malad M, Lakssir I, Issouani J, Guerboub AA.   +4 more
europepmc   +1 more source

Characterization of pediatric eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis in a nationwide cohort

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 531-540, February 2026.
Abstract Objectives Nonesophageal eosinophilic gastrointestinal disorders (non‐EoE EGIDs) are rare, underrecognized inflammatory diseases of the gastrointestinal (GI) tract, especially in children. Their clinical heterogeneity and lack of specific biomarkers contribute to diagnostic delays and therapeutic challenges.
Sara Renzo, Luca Scarallo, Selene Del Vespa, Giulia Angelino, Matteo Bramuzzo, Enrico Felici, Flavio Labriola, Francesca Laganà, Lorenzo Norsa, Salvatore Oliva, Marisa Piccirillo, Elena Pozzi, Francesca Rea, Giusy Russo, Francesco Valitutti, Giovanna Zuin, Paolo Lionetti   +16 more
wiley   +1 more source

Transcriptomics identified crucial candidate genes and pathways regulating early testicular development of drakes in the hypothalamic-pituitary-gonadal/thyroid axes. [PDF]

BMC Genomics
Chen Y, Hu X, Chi X, Lin Y, Lin R, Chen H, Cai K, Chen F, Ye X, Li X, Ouyang Q, Li J, Zhu L, Liu H, Hu J, Li L, Wang J.   +16 more
europepmc   +1 more source