Results 131 to 140 of about 286,655 (306)

Guideline for the In Vivo Immunomodulatory Activity Test of Polysaccharide Based on Cyclophosphamide‐Induced Mouse Model

Food Safety and Health, EarlyView.
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie, Xuecong Tong, Qiao Ding, Xiaojun Huang   +3 more
wiley   +1 more source

Pubertal timing and incident uterine cancer in the Sister Study cohort

International Journal of Cancer, EarlyView.
What's New? Younger age at menarche is an established risk factor for uterine cancer. Age at onset of breast development (thelarche), the earliest marker of pubertal estrogen exposure unopposed by progesterone, may also be relevant to uterine cancer risk, but this association has not been explored. Using data from the US prospective Sister Study cohort,
Ariayana N. Harrell, Katie M. O'Brien, Natalie D. Shaw, Dale P. Sandler, Mandy Goldberg   +4 more
wiley   +1 more source

Presentation and Management of Addison's Disease in a 10‐Year‐Old Boy: A Case Report

iLABMED, EarlyView.
ABSTRACT Addison's disease, or primary adrenal insufficiency, is a rare endocrine disorder characterized by impaired adrenal hormone production. We report a case of a 10‐year‐old boy with congenital adrenal hyperplasia and secondary Addison's disease on long‐term corticosteroid therapy who presented with recurrent non‐bilious vomiting, low‐grade fever,
Srinivasan Sivannan, Mohammed Azhar Hussain, Syed Mohammed Hussaini, Pasumarthi Tejashree, Karthikeyan Elumalai   +4 more
wiley   +1 more source

McCune Albright Syndrome [PDF]

, 2020
Jibbe, Atieh, Jibbe, Nada, Rajpara, Anand   +2 more
core   +2 more sources

SPARK: A webserver for comprehensive search and analysis of testicular single‐cell transcriptomic data covering full lifecycle and pathology

iMetaOmics, EarlyView.
SPARK is an interactive platform hosting 189,232 human testicular single‐cell transcriptomes across normal and infertile conditions. It enables automated, code‐free analysis and visualization, providing a powerful resource to explore cellular and molecular dynamics in male reproduction and infertility.
Lina Cui, Xiaojian Lu, Hui Cai, Ziyan Zhuang, Yifei Guo, Qiaoling Jiang, Zhe Zhang, Hui Jiang, Xiaoyan Wang, Jingtao Guo   +9 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Bridging Early Adolescents' Online and In‐Person Experiences: Qualitative Explorations of Emotional and Relational Well‐Being in the Post‐COVID‐19 Era

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Technology plays a dual role in adolescents' lives, offering valuable avenues for social engagement and support while also introducing risks of social comparison, harassment, and loneliness. Qualitative data that centers on adolescent voices and contexts can illuminate the interplay of these protective and risk factors.
Xiaoqi Ma, Marielena R. McWhirter Boisen, Cassidy Dillard, Yeseul Lee, Ella Absalon, Jennifer L. Doty   +5 more
wiley   +1 more source

Sensory Processing Sensitivity: Associations With Psychological Well‐Being and Sleep Health Among Adolescent Girls

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Adolescence is associated with risks for sleep and mental health issues, particularly among girls. Identifying risk factors is essential for designing targeted interventions during this vulnerable developmental period. One factor to consider is Sensory Processing Sensitivity (SPS), the ability to adapt and respond to one's ...
Julianna P. Adornetti, Nikoo Karbassi, Abaigeal L. Houlihan, Emily M. Smith, Hannah Hagy, Amy M. Bohnert   +5 more
wiley   +1 more source

Young people's lived experience expertise: Insights from the DigiCAT project to develop a counterfactual analysis tool for mental health data

JCPP Advances, EarlyView.
In our project to develop a digital tool for counterfactual analysis, with an emphasis on researching active ingredients for adolescent mental health, we incorporated lived experience expertise across the lifecycle of tool development and dissemination.
Marie Allitt, Helen Wright, Aja Murray, Ingrid Obsuth   +3 more
wiley   +1 more source

The dynamic interplay between mental health difficulties and the family environment in early adolescence

JCPP Advances, EarlyView.
This paper unravels relationships between adolescent mental health and family environment factors. We find that emotional problems in adolescence predict both hyperactivity/inattention and sibling problems over time. Abstract Background Adolescents experiencing mental health problems have an elevated risk of persisting difficulties as they transition ...
Ludvig Daae Bjørndal, Omid V. Ebrahimi, Sarah Bauermeister   +2 more
wiley   +1 more source