Brief Report: Is Gestational Exposure to HIV and Protease Inhibitors Associated With Timing of Pubertal Onset? [PDF]
Serghides L +9 more
europepmc +1 more source
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
Management strategies for isolated premature thelarche: a risk-stratified clinical pathway favoring "watchful waiting". [PDF]
Xu Y, Cui H, Wang X, Liu F.
europepmc +1 more source
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
History of and evidence for puberty suppression as intervention for children experiencing gender dysphoria. [PDF]
Biggs M.
europepmc +1 more source
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source
Activity Changes of the Hypothalamus-Pituitary Hormonal Axis in Peripubertal Female Rats. [PDF]
Jeon EY, Lee SH.
europepmc +1 more source
Pharmacogenetics of follicle‐stimulating hormone action in the male
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani +7 more
wiley +1 more source
Abstract Background The stretched penile length is recognized as the most reliable measure of true penile size, this fact is not widely acknowledged, and societal myths often associate penile length with other anthropometric measurements. While markers of prenatal androgen exposure, such as anogenital distance and the second‐to‐fourth digit ratio (2D ...
Coşkun Kaya +5 more
wiley +1 more source
Longer Breastfeeding Is Associated With Healthier Body Mass Index Trajectories and Lower Risk of Overweight and Obesity in Youth Aged 9-12 Years. [PDF]
Ottino González J +4 more
europepmc +1 more source

