Results 81 to 90 of about 18,258,000 (310)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Correction: COVID-19 vaccination implementation in six lower- and middle-income countries: Successes, challenges, and lessons for pandemic preparedness.

PLOS Global Public Health
[This corrects the article DOI: 10.1371/journal.pgph.0004417.].
PLOS Global Public Health Staff
doaj   +1 more source

RWU Law, LPI Study Finds Issuing Driver\u27s Licenses to Undocumented Rhode Islanders Would Mean Safer Roads [PDF]

, 2017
Legal and policy analysis by RWU School of Law and Latino Policy Institute also finds poverty rates fall faster in states providing undocumented immigrants with ...
Public Affairs, Roger Williams University
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Correction: Pre-exposure prophylaxis (PrEP) awareness, use, and discontinuation among Lake Victoria fisherfolk in Uganda: A cross-sectional population-based study.

PLOS Global Public Health
[This corrects the article DOI: 10.1371/journal.pgph.0003994.].
PLOS Global Public Health Staff
doaj   +1 more source

RWU Announces $500,000 Gift to Establish Hassenfeld Projects [PDF]

, 2016
Transformative gift will deploy more students throughout Rhode Island to meet local community ...
Public Affairs, Roger Williams University
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

ProJo Veteran Ed Fitzpatrick Named RWU’s New Director of Media and Public Relations [PDF]

, 2016
Veteran journalist brings 28 years of experience as reporter, editor and columnist to new position at the ...
Public Affairs, Roger Williams University
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Inaugural Poet Richard Blanco to Share His Works at RWU on April 15 [PDF]

, 2014
Public invited to free President’s Distinguished Speakers Series event with acclaimed Cuban-American poet Richard ...
Public Affairs, Roger Williams University
core   +1 more source