Results 181 to 190 of about 4,284,812 (296)

STRATEGIC MANAGEMENT – MODEL AND TOOL FOR THE DEVELOPMENT OF THE LOCAL COMMUNITIES MANAGEMENT, IN THE STATE REFORM CONTEXT [PDF]

open access: yes
Ever since 2007, along with the completion of the EU accession process, but also before that, our country has constantly focused on improving local government standards either through a solid and sustained reform or through public system management ...
Ana Claudia TAPARDEL
core  

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

ANALYSIS OF THE MANAGEMENT AT THE LEVEL OF PUBLIC ADMINISTRATION IN ROMANIA [PDF]

open access: yes
The transition dynamic, the status of the Member State of the European Union, as well as the current global economic crisis context, determined new challenges for the Romanian public administration.
Marius Constantin PROFIROIU
core  

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

REFORMING THE PUBLIC ADMINISTRATION THROUGH E-GOVERNMENT: A REGIONAL APPROACH [PDF]

open access: yes
The aim of this study is to disclose the progress in reforming the public administration through e-government from a regional point of view. The study has revealed that European regions have good performances in e-government development. However, Romania
Monica Daniela TESU (PASCULESCU)
core  

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh   +8 more
wiley   +1 more source

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