Results 31 to 40 of about 10,635,887 (365)

The COVID-19 pandemic as a game changer for public administration and leadership? The need for robust governance responses to turbulent problems

, 2020
The COVID-19 pandemic reveals that the public sector is not only facing simple and complex problem, but also turbulent problems characterized by the surprising emergence of inconsistent, unpredictable, and uncertain events.
C. Ansell, E. Sørensen, J. Torfing
semanticscholar   +1 more source

Rationalization of public administration [PDF]

Војно дело, 2016
In the European Union, special attention is addressed to the area of public administration, which, according to opinions of many, is its fourth fundamental pillar.
Đorđević Zoran N., Trandafilović Saša K.   +1 more
doaj   +1 more source

Problems and Prospects of Chinese Infrastructure Construction and Investment Activity in Latin America

RUDN Journal of Public Administration, 2023
The article is devoted to the peculiarities of economic relations between China and Latin American countries at the present stage. The characteristic features of trade relations and the implementation of joint infrastructure projects were revealed. There
Svetlana V. Batanova
doaj   +1 more source

Abductive analysis in qualitative public administration research

PAR. Public Administration Review
Public administration scholars and practitioners need to know how state‐of‐the‐art research is conducted. This article aims to contribute to the dialogue on qualitative analysis.
Merlijn van Hulst, E. L. Visser
semanticscholar   +1 more source

Beyond the State: Global Policy and Transnational Administration

International Review of Public Policy, 2019
The conceptual distance between the sovereign state and the global domain of policy making and administration is narrowing, challenging the prevailing methodological nationalism. The rise of global policy and transnational administration necessitates new
Kim Moloney, Diane Stone
doaj   +1 more source

The Administration of Public Assistance [PDF]

, 1995
This Essay discusses the problems of implementation and administration of proposed welfare reforms. It gives a brief historical background on such reforms, describes the nature of their administration, discusses current and proposed reforms and the ...
Krauskopf, James A.
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The perception of public servants about the practice of the principles LIMPE: a study at the University of Brasilia

Economia & Região, 2021
The aim of this paper is to seek evidence on the perception of public servants of the University of Brasilia regarding the practice of explicit constitutional principles of public administration in the caput of article 37 of the Federal Constitution ...
Alisson Assis de Lima, Luiz Honorato da Silva Júnior   +1 more
doaj  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source