Results 61 to 70 of about 4,284,812 (296)
The Development of the European Administration: Fundamental Concepts and Approaches [PDF]
The study approaches in an unitary manner, the fundamental concepts of the theoretical and practical accomplishment of an European public administration: the European Administrative Space, the convergence and the administrative dynamics and the ...
Matei, Ani.
core +2 more sources
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Public administration megacities in the context mechanisms of public administration
The article analyzes scientific research of public management of megacities in the context of governance mechanisms. Particular emphasis is placed on the correlation of theoretical and practical approaches to determine the effectiveness of public ...
R. A. Makhynia
doaj
Public Administration and Literature
Nowadays Law and Literature courses become more and more popular worldwide; this is also true for Hungary. Examining these attempts, we may conclude that legal problems do reach the students through mainly fictitious literary stories instead of real ...
Ádám Rixer
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Public Administration Reform in the Spirit of Kosovo’s Integration into the European Union [PDF]
The public administration reform in Kosovo can be defined as a challenge to make significant changes in the government, decentralization of public administration, simplification of procedures, computerization of services and electronic governance at all ...
Avdullah Robaj
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
One of the basic problems of Turkish public administration is its distrustfulness against both to the public and its own staff. Similarly, the public don’t trust the public administration which is insensitive to their own expectations, desires and ...
Murat YILDIRIM
doaj
Domestic violence in Australia: interim report [PDF]
One in three Australian women have experienced physical violence since the age of 15 and almost one in five have experienced sexual violence. A study of Victorian women demonstrated that domestic violence is the leading preventable contributor to ...
Senate Finance and Public Administration References Committee
core

