Results 61 to 70 of about 8,382,152 (343)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

The perception of public servants about the practice of the principles LIMPE: a study at the University of Brasilia

open access: yesEconomia & Região, 2021
The aim of this paper is to seek evidence on the perception of public servants of the University of Brasilia regarding the practice of explicit constitutional principles of public administration in the caput of article 37 of the Federal Constitution ...
Alisson Assis de Lima   +1 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Considerations on the Remuneration System of the Public Administration – an Analysis on Electoral Cycles and Scenarios Development [PDF]

open access: yesTheoretical and Applied Economics, 2009
The paper aims to identify trends in the characteristics of the number of employees and the average salary in public administration in the last two election cycles in the period 2000-2008 compared with other sectors and proposes a series of three ...
Tudorel Andrei   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The COVID-19 pandemic as a game changer for public administration and leadership? The need for robust governance responses to turbulent problems

open access: yes, 2020
The COVID-19 pandemic reveals that the public sector is not only facing simple and complex problem, but also turbulent problems characterized by the surprising emergence of inconsistent, unpredictable, and uncertain events.
C. Ansell, E. Sørensen, J. Torfing
semanticscholar   +1 more source

The Research of the Administrative Phenomenon Within the European Space from the Perspective of the Organisms Specialized in Professional Trading

open access: yesEIRP Proceedings, 2011
The problematic of the continuous training, specialization and perfection of professional training of public servants and contractual personnel in the public administration has constituted the reason for which the European Commission sustained the ...
Gina Livioara Goga, Gabriel Gurita
doaj  

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