Results 61 to 70 of about 4,284,812 (296)

The Development of the European Administration: Fundamental Concepts and Approaches [PDF]

open access: yes, 2004
The study approaches in an unitary manner, the fundamental concepts of the theoretical and practical accomplishment of an European public administration: the European Administrative Space, the convergence and the administrative dynamics and the ...
Matei, Ani.
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Public administration megacities in the context mechanisms of public administration

open access: yesAspekti Publìčnogo Upravlìnnâ, 2014
The article analyzes scientific research of public management of megacities in the context of governance mechanisms. Particular emphasis is placed on the correlation of theoretical and practical approaches to determine the effectiveness of public ...
R. A. Makhynia
doaj  

Public Administration and Literature

open access: yesPublic Governance, Administration and Finances Law Review, 2017
Nowadays Law and Literature courses become more and more popular worldwide; this is also true for Hungary. Examining these attempts, we may conclude that legal problems do reach the students through mainly fictitious literary stories instead of real ...
Ádám Rixer
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Public Administration Reform in the Spirit of Kosovo’s Integration into the European Union [PDF]

open access: yesKrytyka Prawa
The public administration reform in Kosovo can be defined as a challenge to make significant changes in the government, decentralization of public administration, simplification of procedures, computerization of services and electronic governance at all ...
Avdullah Robaj
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

AN EVALUATION OF THE PROBLEMS OF TURKISH PUBLIC ADMINISTRATION FROM THE POINT OF VIEW OF PUBLIC RELATIONS

open access: yesZeitschrift für die Welt der Türken, 2010
One of the basic problems of Turkish public administration is its distrustfulness against both to the public and its own staff. Similarly, the public don’t trust the public administration which is insensitive to their own expectations, desires and ...
Murat YILDIRIM
doaj  

Domestic violence in Australia: interim report [PDF]

open access: yes
One in three Australian women have experienced physical violence since the age of 15 and almost one in five have experienced sexual violence.  A study of Victorian women demonstrated that domestic violence is the leading preventable contributor to ...
Senate Finance and Public Administration References Committee
core  

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