Results 91 to 100 of about 2,772,427 (357)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

International best-shot public goods and foreign aid [PDF]

open access: yes
This note corrects an analytical mistake of Jayaraman and Kanbur (1999) in their analysis of a Stackelberg game of the voluntary contribution to an international best-shot public good by a donor and a recipient.
Xiaopeng Xu
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Remittances, Public Health Spending and Foreign Aid in the Access to Health Care Services in Developing Countries [PDF]

open access: yes
The aim of this paper is to analyze the respective impacts of remittances, health aid and public spending on the access to health care services in developing countries. The specific objectives are threefold.
Alassane DRABO, Christian EBEKE
core  

A Regional Assessment of Borough Government Finances And Employment [PDF]

open access: yes, 2017
Alaska’s state budget revenues declined by more than 90% from 2012 to 2016, mainly due to a sharp drop in oil prices: oil revenues have paid for most state government operations since the 1980s.
Guettabi, Mouhcine
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Imaging pitfalls in fragility fractures of the pelvis: a case series

open access: yesJournal of Medical Case Reports
Background Fragility fractures of the pelvis are low-energy pelvic ring fractures commonly occurring in older adults. Early diagnosis of fragility fractures of the pelvis is important because of the possibility of fracture progression and deterioration ...
Koyo Tsutsumi   +6 more
doaj   +1 more source

Secondary Fat Grafting in Breast Reconstruction: Comparison Between After Autologous Flap and After Silicone Implant

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. This study aimed to evaluate the impact of secondary fat grafting on patient satisfaction and well-being using the BREAST-Q, in patients who underwent flap- or implant-based breast reconstruction. Methods:.
Takanobu Mashiko, MD   +3 more
doaj   +1 more source

The fiscal impact of foreign aid in Rwanda : a theoretical and empirical analysis [PDF]

open access: yes
The inflow of large quantities of foreign aid into Rwanda since 1994 can have potential adverse effects such as aid dependency via a significant negative effect on tax efforts and on public investments.
Ezemenari, Kene   +2 more
core  

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