Results 21 to 30 of about 214,419 (262)
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUAThe impact of urban noise pollution on billions of people across the globe is not yet enough to enable the adoption of conventional noise-control methods that are based solely on the reduction of sound pressure levels.
Sami Melik +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Benjaminian analysis of the built environment
Acta AcademicaWalter Benjamin was a critical theorist and lover of architecture, and he spent most of his career studying urban spaces and places. In this paper, we use his theory of architecture to develop a normative critique that can be used to analyse public ...
Nathisvan Govender, Cate Otto
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Universal Design Principles Applied in Museums’ Historic Buildings
Prostor, 2022 Museums represent an architecturally multifaceted typology. Regardless of their variant focus, their current task is to provide an opportunity for cultural, educational, and exploratory experience for all. The accessibility of the physical environment is
Natália Filová +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Modern Port-Industrial Town of Ploče, Croatia
ProstorPloče is the only town in Croatia that was planned and built on the Adriatic coast as a result of social planning after World War II. As a planned port-industrial town, Ploče has been neglected in architectural research by experts and the wider public ...
Zrinka Barišić Marenić +2 more
doaj +1 more source