Results 261 to 270 of about 3,335,885 (354)

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

open access: yesAdvanced Intelligent Systems, EarlyView.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger   +6 more
wiley   +1 more source

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

open access: yesAdvanced Intelligent Systems, EarlyView.
FTGRN introduces an LLM‐enhanced framework for gene regulatory network inference through a two‐stage workflow. It combines a Transformer‐based model, pretrained on GPT‐4 derived gene embeddings and regulatory knowledge, with a fine‐tuning stage utilizing single‐cell RNA‐seq data.
Guangzheng Weng   +7 more
wiley   +1 more source

Review of Memristors for In‐Memory Computing and Spiking Neural Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
Memristors uniquely enable energy‐efficient, brain‐inspired computing by acting as both memory and synaptic elements. This review highlights their physical mechanisms, integration in crossbar arrays, and role in spiking neural networks. Key challenges, including variability, relaxation, and stochastic switching, are discussed, alongside emerging ...
Mostafa Shooshtari   +2 more
wiley   +1 more source

Multivariate Contrastive Predictive Coding with Sliding Windows for Disease Prediction from Electronic Health Records

open access: yesAdvanced Intelligent Systems, EarlyView.
Adaptive multi‐indicator contrastive predictive coding is introduced as a self‐supervised pretraining framework for multivariate EHR time series. An adaptive sliding‐window algorithm and 2D convolutional neural network encoder capture localized temporal patterns and global indicator dependencies, enabling label‐efficient disease prediction that ...
Hongxu Yuan   +3 more
wiley   +1 more source

AI Guided Protein Design for Next‐Generation Autogenic Engineered Living Materials

open access: yesAdvanced Intelligent Systems, EarlyView.
Autogenic engineered living materials (ELMs) integrate biology and materials science to create self‐regenerating and self‐healing materials. This perspective highlights emerging strategies in protein engineering and AI‐guided de novo design to expand the capabilities of autogenic ELMs.
Hoda M. Hammad, Anna M. Duraj‐Thatte
wiley   +1 more source

Enhancing Atomic‐Resolution in Electron Microscopy: A Deep Learning Denoiser Operating in the Frequency Domain

open access: yesAdvanced Intelligent Systems, EarlyView.
The newly developed AI‐automated Fast Fourier Transform denoising algorithm surpasses conventional real‐space methods by revealing even light atoms otherwise hidden in noisy backgrounds. Atomic resolution electron microscopy has become an essential tool for many scientific fields, when direct visualization of atomic arrangements and defects is needed ...
Ivan Pinto‐Huguet   +8 more
wiley   +1 more source

Voxel‐SLAM: A Complete, Accurate, and Versatile Light Detection and Ranging‐Inertial Simultaneous Localization and Mapping System

open access: yesAdvanced Intelligent Systems, EarlyView.
: In this work, Voxel‐SLAM (simultaneous localization and mapping) is introduced: a complete, accurate, and versatile LiDAR (light detection and ranging) ‐inertial SLAM system consisting of five modules: initialization, odometry, local mapping (LM), loop closure (LC), and global mapping (GM), all employing the same map representation, an adaptive voxel
Zheng Liu   +9 more
wiley   +1 more source

Building an Intelligent Cardiovascular System Platform: Embedding Artificial Intelligence across All Facets of Cardiovascular Medicine

open access: yesAdvanced Intelligent Systems, EarlyView.
This paper presents an integrated AI‐driven cardiovascular platform unifying multimodal data, predictive analytics, and real‐time monitoring. It demonstrates how artificial intelligence—from deep learning to federated learning—enables early diagnosis, precision treatment, and personalized rehabilitation across the full disease lifecycle, promoting a ...
Mowei Kong   +4 more
wiley   +1 more source

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