BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao +9 more
wiley +1 more source
Hysteroscopic ablation of type 2 and type 3 fibroids using radiofrequency or microwave energy. [PDF]
Manzi A +7 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
The politics of integrating health systems and public programs: a review of political headwinds, tailwinds, and policy maker recommendations. [PDF]
Kavanagh NM, Menon A, McIntyre A.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Cancer Survivorship Practices Among Cancer Care Providers and Cancer Centers in Brazil: Results From a National Survey. [PDF]
Barbosa Carroll C +5 more
europepmc +1 more source
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv +12 more
wiley +1 more source
Interprofessional Perspective: Development of the National Academies of Practice Joint Health Literacy Position Statement. [PDF]
Wagner T +8 more
europepmc +1 more source
Best practices from the Association of Pulmonary and Critical Care Medicine Program Directors for social media use with emphasis on virtual recruitment. [PDF]
Greco AA +6 more
europepmc +1 more source

