Results 51 to 60 of about 4,570,917 (333)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Fidelity of the Guided Self-Determination program in the MyHealth study during breast cancer follow-up

Acta Oncologica
Background and purpose: MyHealth is a new follow-up program including individual nurse-led sessions based on Guided Self-Determination (GSD), which has been shown to improve health and psychological outcomes in patients after treatment for breast cancer.
Sigrid N. Biener, Beverley L. Høeg, Lena Saltbæk, Susanne O. Dalton, Christoffer Johansen, Randi V. Karlsen, Federica Belmonte, Vibeke Zoffmann, Pernille E. Bidstrup   +8 more
doaj   +1 more source

Releasing Graph Neural Networks with Differential Privacy Guarantees [PDF]

Transactions on Machine Learning Research (TMLR), 2023, 2021
With the increasing popularity of graph neural networks (GNNs) in several sensitive applications like healthcare and medicine, concerns have been raised over the privacy aspects of trained GNNs. More notably, GNNs are vulnerable to privacy attacks, such as membership inference attacks, even if only black-box access to the trained model is granted.
arxiv  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

The veterinary profession and one medicine: some considerations, with particular reference to Italy [PDF]

Veterinaria Italiana, 2011
The concept of ‘one medicine’ and its evolution are discussed and some considerations on the relationship between ‘one medicine’ and veterinary profession are made, with particular reference to Italy.
Giorgio Battelli, Adriano Mantovani
doaj  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

An Ontology-driven Treatment Article Retrieval System for Precision Oncology [PDF]

arXiv, 2020
This paper presents an ontology-driven treatment article retrieval system developed and experimented using the data and ground truths provided by the TREC 2017 precision medicine track. The key aspects of our system include: meaningful integration of various disease, gene, and drug name ontologies, training of a novel perceptron model for article ...
arxiv  

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Impaired autophagy-accelerated senescence of alveolar type II epithelial cells drives pulmonary fibrosis induced by single-walled carbon nanotubes

Journal of Nanobiotechnology, 2023
Background The rapid increase in production and application of carbon nanotubes (CNTs) has led to wide public concerns in their potential risks to human health.
Xiang Zhang, Xinxin Hu, Yuqing Zhang, Bin Liu, Haihong Pan, Zikai Liu, Zhuomeng Yao, Qixing Zhu, Changhao Wu, Tong Shen   +9 more
doaj   +1 more source