Results 71 to 80 of about 4,451,019 (394)

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Molecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee   +8 more
wiley   +1 more source

The veterinary profession and one medicine: some considerations, with particular reference to Italy [PDF]

Veterinaria Italiana, 2011
The concept of ‘one medicine’ and its evolution are discussed and some considerations on the relationship between ‘one medicine’ and veterinary profession are made, with particular reference to Italy.
Giorgio Battelli, Adriano Mantovani
doaj  

Impaired autophagy-accelerated senescence of alveolar type II epithelial cells drives pulmonary fibrosis induced by single-walled carbon nanotubes

Journal of Nanobiotechnology, 2023
Background The rapid increase in production and application of carbon nanotubes (CNTs) has led to wide public concerns in their potential risks to human health.
Xiang Zhang, Xinxin Hu, Yuqing Zhang, Bin Liu, Haihong Pan, Zikai Liu, Zhuomeng Yao, Qixing Zhu, Changhao Wu, Tong Shen   +9 more
doaj   +1 more source

Bio-psycho-social medicine is a comprehensive form of medicine bridging clinical medicine and public health

BioPsychoSocial Medicine, 2010
The journal, BioPsychoSocial Medicine, was launched in January 2007, and more than three and a half years have passed since the start of publication.
M. Nakao
semanticscholar   +1 more source

Cardiovascular Diseases Prevention and Control [PDF]

, 2008
The CVD (heart disease and stroke, atherosclerosis, high blood pressure) today are the cause of the greatest public health pandemic globally in the history of the world ever, with very high morbidity and death rate, and economical and social consequences.
Donev, Doncho, Sadikario, Samuel, Zaletel Kragelj, Lijana   +2 more
core   +2 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Narrowing the gap of personalized medicine in emerging countries: the case of multiple endocrine neoplasias in Brazil [PDF]

, 2012
The finished version of the human genome sequence was completed in 2003, and this event initiated a revolution in medical practice, which is usually referred to as the age of genomic or personalized medicine.
Coutinho, Flavia L., Longuini, Viviane C., Lourenço Jr., Delmar M., Sekiya, Tomoko, Toledo, Rodrigo A., Toledo, Sergio P. A.   +5 more
core   +11 more sources

Current Issues in Sport Science

Current Issues in Sport Science, 2022
CISS welcomes and encourages articles addressing a broad range of topics across sport science which include but is not limited to genetic, biological, physical, physiological, psychological, pedagogical, sociological, environmental, policy among other ...
Claudio Nigg, Markus Tilp, Günter Amesberger, Carol Ewing Garber, Thomas Finkenzeller, Martin Keller, Christine Pellegrini, Sebastian Ruin, Thorsten Stein, Ansgar Thiel, Mireille van Poppel, Sabine Würth   +11 more
doaj   +1 more source

A Comparative Analysis of Attitudes on Communication Toward Stem Cell Research and Regenerative Medicine Between the Public and the Scientific Community

Stem Cells Translational Medicine, 2018
Owing to the rapid progress in stem cell research (SCR) and regenerative medicine (RM), society's expectation and interest in these fields are increasing.
Ryuma Shineha, Yusuke Inoue, Tsunakuni Ikka, A. Kishimoto, Yoshimi Yashiro   +4 more
semanticscholar   +1 more source

Dying like a dog: the convergence of concepts of a good death in human and veterinary medicine

Medicine, Health care and Philosophy, 2021
Standard views of good death in human and veterinary medicine considerably differ from one another. Whereas the good death ideal in palliative medicine emphasizes the positive aspects of non-induced dying, veterinarians typically promote a quick and ...
F. Selter, Kirsten Persson, Johanna Risse, P. Kunzmann, G. Neitzke   +4 more
semanticscholar   +1 more source