Results 81 to 90 of about 4,168,338 (311)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Fully Validated, Multi-Kilogram cGMP Synthesis of MDMA

ACS Omega, 2021
Jay B. Nair, Linda Hakes, Berra Yazar-Klosinski, Kathryn Paisner   +3 more
doaj   +1 more source

Acting as a benefit corporation and a B Corp to responsibly pursue private and public benefits. The case of Paradisi Srl (Italy)

International Journal of Corporate Social Responsibility, 2019
Benefit Corporations and B Corps represent alternative models of enterprise that bridge the for-profit and not-for-profit model (hybrid organizations).
Mara Del Baldo
doaj   +1 more source

"Consent Does Not Scale": Laying Out the Tensions in Balancing Patient Autonomy with Public Benefit in Commercializing Biospecimens. [PDF]

J Law Med Ethics, 2023
Spector-Bagdady K.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

PROTECTION OF INDIVIDUAL PROPERTY IN DUBAI REAL ESTATE EXPROPRIATION LAW OF 2022 IN LIGHT OF NARROWING THE CONCEPT OF PUBLIC BENEFIT

Malaysian Journal of Syariah and Law
In light of the rapid urban and cultural renaissance in Dubai and the need to expropriate real estate owned by individuals, this paper discusses the protection of individual property in the Emirate of Dubai Real Estate Expropriation Law of 2022.
Zaid Muhmoud Agaileh
doaj   +1 more source

Navigating data governance associated with real-world data for public benefit: an overview in the UK and future considerations. [PDF]

BMJ Open, 2023
Jones MC, Stone T, Mason SM, Eames A, Franklin M.   +4 more
europepmc   +1 more source

Benefit-Cost Analysis for Transportation Planning and Public Policy: Towards Multimodal Demand Modeling [PDF]

, 2016
This report examines existing methods of benefit-cost analysis (BCA) in two areas, transportation policy and transportation planning, and suggests ways of modifying these methods to account for travel within a multimodal system. Although the planning and
Holian, Matthew, McLaughlin, Ralph
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Sharing real-world data for public benefit: a qualitative exploration of stakeholder views and perceptions. [PDF]

BMC Public Health, 2023
Baxter S, Franklin M, Haywood A, Stone T, Jones M, Mason S, Sterniczuk K.   +6 more
europepmc   +1 more source