Results 101 to 110 of about 758,463 (303)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Migration and Local Public Services [PDF]
Using unique Swedish micro data we examine the impact of local public services on community choice. The choice of community is modeled as a choice between a discrete set of alternatives. The US literature has produced conflicting evidence with respect to
Dahlberg, Matz, Fredriksson, Peter
core
Public employment and income redistribution: causal evidence for Brazilian municipalities
, 2011 Conteúdo online de acesso restrito pelo editorThis paper examines the relationship between public employment and income redistribution in Brazilian municipalities. First, we use the requirements set forth by the Fiscal Responsibility Act as an instrument
Mattos, Enlinson +1 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Public Choice begins with the observation that in politics, as in economics, individuals and institutions compete for scarce resources and that, therefore, the same methods of analyses used by economists to explain the behaviour of consumers and ...
Borooah, Vani
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Public Choice with Unequally Rational Individuals [PDF]
As governments lack the rationality-promoting selective pressures of market competition, the standard (unbounded) rationality assumption is less legitimate in Public Choice than in analysis of markets.
Pelikan, Pavel
core
The Impact of Corporate Political Activity over Strategic Management [PDF]
Revista de Management Comparat International, 2009 At this present rate of supersaturation of the markets, the interaction between economic actors and political officials gains a momentum without precedent.
Simona Buşoi, Amedeo Istocescu
doaj
A model and the behavioral implications of the calculus of consent: The dilemma of public choice before public choice. [PDF]
PLoS One, 2020 Kim M, Park DH.
europepmc +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source