Results 31 to 40 of about 149,143 (217)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Can Public Choice Theory Explain EU Enlargement?
Czech Journal of International Relations, 2005 This paper examines the process of EU enlargement using public choice theory. It starts by outlining the history of EU enlargement, and continues by examining the theoretical approaches to European integration.
Marek Loužek
doaj
Impact of New Institutional Economics on New Public Management
Foundations of ManagementAs pointed out by institutional economics, economic indicators may be improved by social institutions that maintain peace and order. Old Institutional Economics (OIE) believes that government should solve systemic socioeconomic problems according to ...
DEMİREL Demokaan
doaj +1 more source
Urban, Planning and Transport Research, 2023 The aim of this study is to investigate the impacts of COVID-19 pandemic on public transportation mode choices in Ethiopia. Protection motivation theory and multinomial regression model were applied to estimate the mode choice behavior during the ...
Tareke K Moges, Ashebir G Mitiku
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Can Public Choice Theory Explain EU Enlargement?
Czech Journal of International Relations, 2006 This paper applies examines the process of EU enlargement using public choice theory. It starts by outlining the history of EU enlargement, and continues by examining the theoretical approaches to European integration.
Marek Loužek
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Czech Journal of International Relations, 2005 Úskalí veřejné volby. Polemika ke stati Marka Loužka: Dokáže teorie veřejné volby vysvětlit rozšiřování Evropské unie?
Petr Drulák
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source