Results 51 to 60 of about 257,548 (304)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Journal of Deliberative Democracy, 2012 In failed or failing states, deliberation as it is operationalized in much of the political communication literature is inapplicable. These states lack advanced communication infrastructures, press systems and public spheres, which require high literacy ...
Shawn M. Powers, William Youmans
doaj +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Journal of Deliberative Democracy, 2015 This essay focuses on how public deliberation is used as a tool for managing the commons. Through the lens of Elinor Ostrom’s research of managing the commons, the Bloomington Community Orchard is analyzed as a case study to better understand the value ...
Lisa-Marie Napoli
doaj +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Elementy demokracji deliberacyjnej jako sposób na zwiększenie partycypacji obywateli w polskim życiu publicznym [PDF]
, 2017 The participation of citizens in public life, also via deliberation has a positive influence on development of civil society and democracy. citizens’ participation in decision making process increase their influence on important issues of their state ...
Goworek, Katarzyna
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Deliberative Agenda Setting: Piloting Reform of Direct Democracy in California [PDF]
, 2015 Can the people deliberate to set the agenda for direct democracy in large scale states? How might such an institution work? The 2011 California Deliberative Poll piloted a solution to this problem helping to produce proposals that went to the ballot and ...
Fishkin, James +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Affinity Groups, Enclave Deliberation, and Equity
Journal of Deliberative Democracy, 2016 There is growing appreciation for the value of holding enclave dialogue and deliberation among marginalized peoples in their own affinity groups, as one stage in a larger conversation with the broader public or with public officials.
Carolyne Abdullah +2 more
doaj +2 more sources