Results 51 to 60 of about 11,396,221 (294)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Affinity Groups, Enclave Deliberation, and Equity

Journal of Deliberative Democracy, 2016
There is growing appreciation for the value of holding enclave dialogue and deliberation among marginalized peoples in their own affinity groups, as one stage in a larger conversation with the broader public or with public officials.
Carolyne Abdullah, Chad Raphael, Christopher F. Karpowitz   +2 more
doaj   +2 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Individual autonomy and public deliberation in behavioral public policy

Humanities & Social Sciences Communications
The most successful concept in behavioral public policy (BPP) is nudging, which involves altering choice architecture to leverage people’s biases and heuristics to promote welfare-improving behaviors. However, in recent years, nudging has faced criticism.
Nathanaël Colin-Jaeger, Malte Dold
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

The institutionalisation of populist political discourse and conservative uncivil society in the European Union

Nordicom Review, 2021
This article analyses the ideational features of conservative civil society groups at EU level and compares them to progressive groups. Through a frame analysis of the textual materials of these two types of organisations, I examine their reactions to ...
Ruzza Carlo
doaj   +1 more source

Deliberating together: Public deliberation in the context of the hungarian health insurance reform [PDF]

Society and Economy, 2009
It is most often the case that planners of health care reforms and policies try to solve highly complex, or wicked problems. Issues that have no single experts. Collectively, by gathering many different people and bringing them to genuine deliberation, we can, however, create an emergent understanding and commitment, which helps us to tackle these ...
openaire   +1 more source

Citizen Panels and Opinion Polls: Convergence and Divergence in Policy Preferences

Journal of Deliberative Democracy, 2018
Citizen panels offer an alternative venue for gathering input into the policy-making process. These deliberative exercises are intended to produce more thoughtful and informed inputs into the policy-making process, compared to public opinion polls.
David Kahane, Kristjana Loptson, Shelley Boulianne   +2 more
doaj   +2 more sources