Results 141 to 150 of about 7,127,786 (370)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Nonprofit Governance, Organizational Purposiveness and Design

open access: yesAdministrative Sciences, 2015
The final article published in this Special Issue on nonprofit governance provides a platform for myself as the guest editor in two ways: both to reflect in a Postscript on the editorial process in which I became involved since posting a call for papers,
Antonin Wagner
doaj   +1 more source

Learning to Engage with Interactive Systems: A Field Study on Deep Reinforcement Learning in a Public Museum [PDF]

open access: yesarXiv, 2019
Physical agents that can autonomously generate engaging, life-like behaviour will lead to more responsive and interesting robots and other autonomous systems. Although many advances have been made for one-to-one interactions in well controlled settings, future physical agents should be capable of interacting with humans in natural settings, including ...
arxiv  

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

open access: yesAdvanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin   +15 more
wiley   +1 more source

Transdisciplinary collaborations to highlight media advocacy on climate change impacts on medicinal plants: Evidence from content analysis, and recommendations for action

open access: yesThe Journal of Climate Change and Health, 2023
Medicinal plants have long been part of the healthcare systems of humanity. At least eighty percent of the population in all World Health Organization (WHO) regions report using herbal medicines.
Bernard Appiah   +4 more
doaj  

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing   +7 more
wiley   +1 more source

Patient partner perspectives on compensation: Insights from the Canadian Patient Partner Survey

open access: yesHealth Expectations
Introduction There is a growing role for patients, family members and caregivers as consultants, collaborators and partners in health system settings in Canada. However, compensation for this role is not systematized. When offered, it varies in both type
Roma Dhamanaskar   +5 more
doaj   +1 more source

Instagram and the science museum: a missed opportunity for public engagement

open access: yesJournal of Science Communication, 2019
Science museums are missing an opportunity to promote informal education, scientific literacy, public engagement and public visibility of scientists outside of museum walls via Instagram.
P. Jarreau, N. Dahmen, E. Jones
semanticscholar   +1 more source

Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications

open access: yesAdvanced Materials, EarlyView.
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach   +4 more
wiley   +1 more source

Comparing the acceptability of total diet replacement and food-based low energy diets for type 2 diabetes remission amongst South Asians: a public and patient involvement activity [version 4; peer review: 2 approved, 2 not approved]

open access: yesNIHR Open Research, 2022
Background: With type 2 diabetes prevalence rising, low energy diets (total diet replacement and food-based low energy diets) are increasingly used to induce weight loss and achieve diabetes remission.
Sajda Majeed   +4 more
doaj  

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