Results 221 to 230 of about 5,761,819 (344)

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Exploring the relationship between entertainment and education in anatomy public engagement: A qualitative examination of anatomists' perspectives. [PDF]

Anat Sci Educ
Wilmshurst LD, Clunie L, Brand K, Parsan Chand C, Sanders KA.   +4 more
europepmc   +1 more source

Una revisión del concepto anglosajón public engagement y su equivalencia funcional a los de extensión y vinculación con el medio

, 2016
Paulette Dougnac
openalex   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

"What does the word loneliness mean to you?" Reflections on co-developing public engagement workshops to facilitate discussions of loneliness with older adults from ethnically diverse groups. [PDF]

Res Involv Engagem
Rees J, Sajid M, Steele C, Croker M, Liu W, Matcham F.   +5 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Shaping the future of primary care in Canada: trainee insights on patient and public engagement in health system transformation research. [PDF]

Health Res Policy Syst
Chisholm A, Gilfoyle M, MacNeil M, Melro C.   +3 more
europepmc   +1 more source

Climate Action Program (CAP): A Task-Based Approach to Public Engagement in Environmental Conservation

Addy Arif Bin Mahathir, Ahmed Abdullah Alsukhailah, Zahra Valizadeh Lakeh, Wilson Brooklyn, Willson Juvent Suharyo, M. Bhattacharjee, Noor Ul Amin   +6 more
openalex   +2 more sources

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

Identifying determinants for promoting public engagement via Chinese E-government TikTok in public health emergencies. [PDF]

PLoS One
Guo J, Wirza Mohd Zawawi J, Kamarudin S.
europepmc   +1 more source